PDB entry 3kw5

View 3kw5 on RCSB PDB site
Description: Crystal structure of ubiquitin carboxy terminal hydrolase L1 bound to ubiquitin vinylmethylester
Class: hydrolase/signaling protein
Keywords: enzyme-suicide substrate complex, hydrolase, ligase, protease, thiol protease, UBL conjugation pathway, isopeptide bond, UBL conjugation, hydrolase-hydrolase inhibitor complex, Acetylation, Cytoplasm, Disease mutation, Glycoprotein, Oxidation, Polymorphism, Nucleus, Phosphoprotein, HYDROLASE-SIGNALING PROTEIN complex
Deposited on 2009-11-30, released 2010-06-16
The last revision prior to the SCOPe 2.05 freeze date was dated 2010-06-16, with a file datestamp of 2010-06-11.
Experiment type: XRAY
Resolution: 2.83 Å
R-factor: 0.235
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin carboxyl-terminal hydrolase isozyme L1
    Species: Homo sapiens [TaxId:9606]
    Gene: PGP9.5, UCHL1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3kw5a_
  • Chain 'B':
    Compound: Ubiquitin
    Species: Homo sapiens [TaxId:9606]
    Gene: RPS27A, UBA52, UBA80, UBB, UBC, UBCEP1, UBCEP2, UBIQ_HUMAN
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3kw5b_
  • Heterogens: GVE

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3kw5A (A:)
gplgsmqlkpmeinpemlnkvlsrlgvagqwrfvdvlgleeeslgsvpapacallllfpl
taqhenfrkkqieelkgqevspkvyfmkqtignscgtiglihavannqdklgfedgsvlk
qflsetekmspedrakcfekneaiqaahdavaqegqcrvddkvnfhfilfnnvdghlyel
dgrmpfpvnhgassedtllkdaakvcreftereqgevrfsavalckaa

    Sequence, based on observed residues (ATOM records): (download) 
    >3kw5A (A:)
mqlkpmeinpemlnkvlsrlgvagqwrfvdvlgleeeslgsvpapacallllfpltaqhe
nfrkkqieelkgqevspkvyfmkqtignscgtiglihavannqdklgfedgsvlkqflse
tekmspedrakcfekneaiqaahdavaqegqcrvddkvnfhfilfnnvdghlyeldgrmp
fpvnhgassedtllkdaakvcreftereqgevrfsavalckaa

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3kw5B (B:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrg