SCOPe 2.01: Structural Classification of Proteins

PDB entry 3krd

View 3krd on RCSB PDB site
Description: Crystal Structure of Mycobacterium Tuberculosis Proteasome in complex with Fellutamide B
Class: hydrolase
Keywords: Binding Sites, Mycobacterium tuberculosis, Protein Subunits, Substrate Specificity, Hydrolase, Proteasome, Fellutamide B, inhibition, Protease, Threonine protease, Virulence, Autocatalytic cleavage, Zymogen
Deposited on 2009-11-18, released 2010-09-29
The last revision prior to the SCOPe 2.01 freeze date was dated 2010-09-29, with a file datestamp of 2010-09-24.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.208
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

Chain '1':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.01: d3krd1_
Chain '2':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245 (0-End)
Domains in SCOPe 2.01: d3krd2_
Chain 'A':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.01: d3krda_
Chain 'B':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.01: d3krdb_
Chain 'C':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245 (0-End)
Domains in SCOPe 2.01: d3krdc_
Chain 'D':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.01: d3krdd_
Chain 'E':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245 (0-End)
Domains in SCOPe 2.01: d3krde_
Chain 'F':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.01: d3krdf_
Chain 'G':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245 (0-End)
Domains in SCOPe 2.01: d3krdg_
Chain 'H':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245 (0-End)
Domains in SCOPe 2.01: d3krdh_
Chain 'I':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.01: d3krdi_
Chain 'J':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245 (0-End)
Domains in SCOPe 2.01: d3krdj_
Chain 'K':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.01: d3krdk_
Chain 'L':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245 (0-End)
Domains in SCOPe 2.01: d3krdl_
Chain 'M':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.01: d3krdm_
Chain 'N':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245 (0-End)
Domains in SCOPe 2.01: d3krdn_
Chain 'O':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.01: d3krdo_
Chain 'P':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245 (0-End)
Domains in SCOPe 2.01: d3krdp_
Chain 'Q':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.01: d3krdq_
Chain 'R':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245 (0-End)
Domains in SCOPe 2.01: d3krdr_
Chain 'S':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.01: d3krds_
Chain 'T':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245 (0-End)
Domains in SCOPe 2.01: d3krdt_
Chain 'U':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.01: d3krdu_
Chain 'V':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245 (0-End)
Domains in SCOPe 2.01: d3krdv_
Chain 'W':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.01: d3krdw_
Chain 'X':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245 (0-End)
Domains in SCOPe 2.01: d3krdx_
Chain 'Y':
Compound: Proteasome subunit alpha
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2169, prcA, Rv2109c
Database cross-references and differences (RAF-indexed):
- Uniprot O33244
Domains in SCOPe 2.01: d3krdy_
Chain 'Z':
Compound: Proteasome subunit beta
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: MT2170, prcB, Rv2110c
Database cross-references and differences (RAF-indexed):
- Uniprot O33245 (0-End)
Domains in SCOPe 2.01: d3krdz_
Heterogens: FEB, HOH

PDB Chain Sequences:

Chain '1':
Sequence, based on SEQRES records: (download)

>3krd1 (1:)
msfpyfispeqamrerselarkgiaraksvvalayaggvlfvaenpsrslqkiselydrv
gfaaagkfnefdnlrrggiqfadtrgyaydrrdvtgrqlanvyaqtlgtifteqakpyev
elcvaevahygetkrpelyritydgsiadephfvvmggttepianalkesyaenasltda
lriavaalragsadtsggdqptlgvaslevavldanrprrafrritgsalqallvdqesp
qsdgessg