PDB entry 3kql

View 3kql on RCSB PDB site
Description: Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism
Class: hydrolase/DNA
Keywords: helicase-substrate transition-state complex, HCV, NS3 protein, helicase, DNA-binding, HYDROLASE-DNA complex
Deposited on 2009-11-17, released 2010-01-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine protease/NTPase/helicase NS3
    Species: Hepatitis C virus [TaxId:333284]
    Gene: NS3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9WMX2 (0-435)
      • expression tag (436)
    Domains in SCOPe 2.08: d3kqla1, d3kqla2, d3kqla3
  • Chain 'B':
    Compound: Serine protease/NTPase/helicase NS3
    Species: Hepatitis C virus [TaxId:333284]
    Gene: NS3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9WMX2 (0-435)
      • expression tag (436)
    Domains in SCOPe 2.08: d3kqlb1, d3kqlb2, d3kqlb3
  • Chain 'E':
    Compound: 5'-d(*tp*tp*tp*tp*tp*t)-3'
  • Chain 'F':
    Compound: 5'-d(*tp*tp*tp*tp*tp*t)-3'
  • Heterogens: ALF, ADP, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3kqlA (A:)
sppavpqtfqvahlhaptgsgkstkvpaayaaqgykvlvlnpsvaatlgfgaymskahgi
dpnirtgvrtittgapitystygkfladggcsggaydiiicdechstdsttilgigtvld
qaetagarlvvlatatppgsvtvphpnieevalsstgeipfygkaipietikggrhlifc
hskkkcdelaaklsglglnavayyrgldvsviptsgdvivvatdalmtgftgdfdsvidc
ntcvtqtvdfsldptftietttvpqdavsrsqrrgrtgrgrmgiyrfvtpgerpsgmfds
svlcecydagcawyeltpaetsvrlraylntpglpvcqdhlefwesvftglthidahfls
qtkqagdnfpylvayqatvcaraqapppswdqmwkclirlkptlhgptpllyrlgavqne
vttthpitkyimacmsa

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3kqlB (B:)
sppavpqtfqvahlhaptgsgkstkvpaayaaqgykvlvlnpsvaatlgfgaymskahgi
dpnirtgvrtittgapitystygkfladggcsggaydiiicdechstdsttilgigtvld
qaetagarlvvlatatppgsvtvphpnieevalsstgeipfygkaipietikggrhlifc
hskkkcdelaaklsglglnavayyrgldvsviptsgdvivvatdalmtgftgdfdsvidc
ntcvtqtvdfsldptftietttvpqdavsrsqrrgrtgrgrmgiyrfvtpgerpsgmfds
svlcecydagcawyeltpaetsvrlraylntpglpvcqdhlefwesvftglthidahfls
qtkqagdnfpylvayqatvcaraqapppswdqmwkclirlkptlhgptpllyrlgavqne
vttthpitkyimacmsa

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.