PDB entry 3kpq

View 3kpq on RCSB PDB site
Description: Crystal Structure of HLA B*4405 in complex with EEYLKAWTF, a mimotope
Class: immune system/peptide
Keywords: HLA B*4405, allorecognition, TCR recognition, mimotope peptide, Disulfide bond, Glycoprotein, Host-virus interaction, Immune response, Membrane, MHC I, Transmembrane, immune system-peptide complex
Deposited on 2009-11-16, released 2009-12-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 1.84 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, B-44 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-B, HLAB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P30481 (0-275)
      • variant (115)
    Domains in SCOPe 2.08: d3kpqa1, d3kpqa2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3kpqb_
  • Chain 'C':
    Compound: EEYLKAWTF, mimotope peptide
    Database cross-references and differences (RAF-indexed):
    • PDB 3KPQ (0-8)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3kpqA (A:)
gshsmryfytamsrpgrgeprfitvgyvddtlfvrfdsdatsprkeprapwieqegpeyw
dretqisktntqtyrenlrtalryynqseagshiiqrmygcdvgpdgrllrgydqyaydg
kdyialnedlsswtaadtaaqitqrkweaarvaeqdrayleglcveslrrylengketlq
radppkthvthhpisdhevtlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdrt
fqkwaavvvpsgeeqrytchvqheglpkpltlrwep

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3kpqB (B:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'C':
    No sequence available.