PDB entry 3kjd

View 3kjd on RCSB PDB site
Description: Human poly(ADP-ribose) polymerase 2, catalytic fragment in complex with an inhibitor ABT-888
Class: transferase
Keywords: transferase, enzyme-inhibitor complex, catalytic fragment, structural genomics, structural genomics consortium, sgc, glycosyltransferase, nad, nucleus, DNA-binding
Deposited on 2009-11-03, released 2009-11-17
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.182
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Poly [ADP-ribose] polymerase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: ADPRT2, ADPRTL2, PARP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UGN5 (23-367)
      • expression tag (14-22)
      • see remark 999 (235)
    Domains in SCOPe 2.07: d3kjda1, d3kjda2, d3kjda3
  • Chain 'B':
    Compound: Poly [ADP-ribose] polymerase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: ADPRT2, ADPRTL2, PARP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UGN5 (23-367)
      • expression tag (11-22)
      • see remark 999 (235)
    Domains in SCOPe 2.07: d3kjdb1, d3kjdb2, d3kjdb3
  • Heterogens: 78P, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3kjdA (A:)
mhhhhhhssgvdlgtenlyfqsmdlrvqeliklicnvqameemmmemkyntkkaplgklt
vaqikagyqslkkiedciragqhgralmeacnefytriphdfglrtpplirtqkelseki
qllealgdieiaiklvktelqspehpldqhyrnlhcalrpldhesyefkvisqylqstha
pthsdytmtlldlfevekdgekeafredlhnrmllwhgsrmsnwvgilshglriahpeap
itgymfgkgiyfadmssksanycfasrlkntgllllsevalgqcnelleanpkaegllqg
khstkglgkmapssahfvtlngstvplgpasdtgilnpdgytlnyneyivynpnqvrmry
llkvqfnf

    Sequence, based on observed residues (ATOM records): (download) 
    >3kjdA (A:)
tenlyfqsmdlrvqeliklicnvqameemmmemkyntkkaplgkltvaqikagyqslkki
edciragqhgralmeacnefytriphdfglrtpplirtqkelsekiqllealgdieiaik
lvkspehpldqhyrnlhcalrpldhesyefkvisqylqsthapthsdytmtlldlfevek
dgekeafredlhnrmllwhgsrmsnwvgilshglriahpeapitgymfgkgiyfadmssk
sanycfasrlkntgllllsevalgqcnelleanpkaegllqgkhstkglgkmapssahfv
tlngstvplgpasdtgilnpdgytlnyneyivynpnqvrmryllkvqfnf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3kjdB (B:)
mhhhhhhssgvdlgtenlyfqsmdlrvqeliklicnvqameemmmemkyntkkaplgklt
vaqikagyqslkkiedciragqhgralmeacnefytriphdfglrtpplirtqkelseki
qllealgdieiaiklvktelqspehpldqhyrnlhcalrpldhesyefkvisqylqstha
pthsdytmtlldlfevekdgekeafredlhnrmllwhgsrmsnwvgilshglriahpeap
itgymfgkgiyfadmssksanycfasrlkntgllllsevalgqcnelleanpkaegllqg
khstkglgkmapssahfvtlngstvplgpasdtgilnpdgytlnyneyivynpnqvrmry
llkvqfnf

    Sequence, based on observed residues (ATOM records): (download) 
    >3kjdB (B:)
dlgtenlyfqsmdlrvqeliklicnvqameemmmemkyntkkaplgkltvaqikagyqsl
kkiedciragqhgralmeacnefytriphdfglrtpplirtqkelsekiqllealgdiei
aiklvktelqspehpldqhyrnlhcalrpldhesyefkvisqylqsthapthsdytmtll
dlfevekdgekeafredlhnrmllwhgsrmsnwvgilshglriahpeapitgymfgkgiy
fadmssksanycfasrlkntgllllsevalgqcnelleanpkaegllqgkhstkglgkma
pssahfvtlngstvplgpasdtgiytlnyneyivynpnqvrmryllkvqfnf