PDB entry 3k9x

View 3k9x on RCSB PDB site
Description: X-ray crystal structure of human fxa in complex with (S)-N-((2-METHYLBENZOFURAN-5-YLAMINO)(2-OXO-1-(2-OXO-2- (PYRROLIDIN-1-YL)ETHYL)AZEPAN-3- YLAMINO)METHYLENE)NICOTINAMIDE
Class: hydrolase
Keywords: SERINE PROTEASE, HYDROLASE, EPIDERMAL GROWTH FACTOR LIKE DOMAIN, BLOOD COAGULATION FACTOR, CLEAVAGE ON PAIR OF BASIC RESIDUES, EGF-LIKE DOMAIN, GAMMA-CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, HYDROXYLATION, ZYMOGEN, BLOOD CLOTTING, Blood coagulation, Disulfide bond, Protease, Secreted
Deposited on 2009-10-16, released 2009-12-15
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.177
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protein (coagulation factor x)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3k9xa1, d3k9xa2
  • Chain 'B':
    Compound: protein (coagulation factor x)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3k9xb_
  • Chain 'C':
    Compound: protein (coagulation factor x)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3k9xc1, d3k9xc2
  • Chain 'D':
    Compound: protein (coagulation factor x)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3k9xd_
  • Heterogens: GOL, MBM, CA, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3k9xA (A:)
kdgdqcetspcqnqgkckdglgeytctclegfegkncelftrklcsldngdcdqfcheeq
nsvvcscargytladngkaciptgpypcgkqtle

    Sequence, based on observed residues (ATOM records): (download) 
    >3k9xA (A:)
cetspcqnqgkckdeytctclegfegkncelftrklcsldngdcdqfcheeqnsvvcsca
rgytladngkaciptgpypcgkqtle

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3k9xB (B:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktrglp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3k9xC (C:)
kdgdqcetspcqnqgkckdglgeytctclegfegkncelftrklcsldngdcdqfcheeq
nsvvcscargytladngkaciptgpypcgkqtle

    Sequence, based on observed residues (ATOM records): (download) 
    >3k9xC (C:)
pcqnqgkckdytctclegfegkncelftrklcsldngdcdqfcheeqnsvvcscargytl
adngkaciptgpypcgkqtle

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3k9xD (D:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktrglp