PDB entry 3k5v

View 3k5v on RCSB PDB site
Description: Structure of Abl kinase in complex with imatinib and GNF-2
Class: transferase
Keywords: kinase, ATP-binding, Nucleotide-binding, Oncogene, SH2 domain, Transferase, Tyrosine-protein kinase
Deposited on 2009-10-08, released 2010-01-19
The last revision prior to the SCOPe 2.02 freeze date was dated 2011-04-06, with a file datestamp of 2011-04-01.
Experiment type: XRAY
Resolution: 1.74 Å
R-factor: 0.201
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase ABL1
    Species: Mus musculus [TaxId:10090]
    Gene: Abl, Abl1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00520 (6-End)
      • expression tag (1-5)
    Domains in SCOPe 2.02: d3k5va_
  • Chain 'B':
    Compound: Tyrosine-protein kinase ABL1
    Species: Mus musculus [TaxId:10090]
    Gene: Abl, Abl1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00520 (6-End)
      • expression tag (2-5)
    Domains in SCOPe 2.02: d3k5vb_
  • Heterogens: STJ, STI, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3k5vA (A:)
gamdpsspnydkwemertditmkhklgggqygevyegvwkkysltvavktlkedtmevee
flkeaavmkeikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevsavvlly
matqissameylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfp
ikwtapeslaynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpe
gcpekvyelmracwqwnpsdrpsfaeihqafetmfqessisdevekelgkrgt

    Sequence, based on observed residues (ATOM records): (download) 
    >3k5vA (A:)
amdpsspnydkwemertditmkhklgggqygevyegvwkkysltvavktlkedmeveefl
keaavmkeikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevsavvllyma
tqissameylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpik
wtapeslaynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegc
pekvyelmracwqwnpsdrpsfaeihqafetmfqessisdevekel

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3k5vB (B:)
gamdpsspnydkwemertditmkhklgggqygevyegvwkkysltvavktlkedtmevee
flkeaavmkeikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevsavvlly
matqissameylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfp
ikwtapeslaynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpe
gcpekvyelmracwqwnpsdrpsfaeihqafetmfqessisdevekelgkrgt

    Sequence, based on observed residues (ATOM records): (download) 
    >3k5vB (B:)
mdpsspnydkwemertditmkhklgggqygevyegvwkkysltvavktlkmeveeflkea
avmkeikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevsavvllymatqi
ssameylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwta
peslaynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpek
vyelmracwqwnpsdrpsfaeihqafetmfqessisdevekel