PDB entry 3jzb

View 3jzb on RCSB PDB site
Description: Crystal Structure of TR-alfa bound to the selective thyromimetic TRIAC
Class: transcription
Keywords: triac, TR, thyroid, entropy, DNA-binding, Metal-binding, Nucleus, Receptor, Transcription, Transcription regulation, Zinc-finger
Deposited on 2009-09-23, released 2009-12-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-09-01, with a file datestamp of 2010-08-27.
Experiment type: XRAY
Resolution: 2.01 Å
R-factor: 0.173
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: THRA protein
    Species: Homo sapiens [TaxId:9606]
    Gene: THRA, hCG_1749555
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6FH41 (4-End)
      • expression tag (0-3)
    Domains in SCOPe 2.08: d3jzba1, d3jzba2
  • Heterogens: 4HY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3jzbA (A:)
    gshmeemirslqqrpeptpeewdlihiateahrstnaqgshwkqrrkflpddigqspivs
    mpdgdkvdleafseftkiitpaitrvvdfakklpmfselpcedqiillkgccmeimslra
    avrydpesdtltlsgemavkreqlkngglgvvsdaifelgkslsafnlddtevallqavl
    lmstdrsgllcvdkieksqeayllafehyvnhrkhniphfwpkllmkvtdlrmigachas
    rflhmkvecptelfpplflevfedqev
    

    Sequence, based on observed residues (ATOM records): (download)
    >3jzbA (A:)
    gshmeemirslqqrpeptpeewdlihiateahrstnaqgshwkqrrkflpddigqspivs
    mpdgdkvdleafseftkiitpaitrvvdfakklpmfselpcedqiillkgccmeimslra
    avrydpesdtltlsgemavkreqlkngglgvvsdaifelgkslsafnlddtevallqavl
    lmstdrsgllcvdkieksqeayllafehyvnhrkhniphfwpkllmkvtdlrmigachas
    rflhmkvecptelfpplflevfed