PDB entry 3juh

View 3juh on RCSB PDB site
Description: Crystal structure of a mutant of human protein kinase CK2alpha with altered cosubstrate specificity
Class: Transferase
Keywords: eukaryotic protein kinase, ATP-binding, Kinase, Nucleotide-binding, Phosphoprotein, Serine/threonine-protein kinase, Transferase, Wnt signaling pathway
Deposited on 2009-09-15, released 2009-10-20
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-10-26, with a file datestamp of 2011-10-21.
Experiment type: XRAY
Resolution: 1.66 Å
R-factor: 0.158
AEROSPACI score: 0.57 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Casein kinase II subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: csnk2a1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P68400 (Start-334)
      • engineered mutation (65)
      • engineered mutation (162)
    Domains in SCOPe 2.01: d3juha_
  • Chain 'B':
    Compound: Casein kinase II subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: csnk2a1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P68400 (Start-334)
      • engineered mutation (65)
      • engineered mutation (162)
    Domains in SCOPe 2.01: d3juhb_
  • Heterogens: CL, ANP, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3juhA (A:)
msgpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklgrgkysevfeainit
nnekvavkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfehvnntd
fkqlyqtltdydirfymyeilkaldychsmgimhrdvkphnvlidhehrklrlidwglae
fyhpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnyd
qlvriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdf
ldkllrydhqsrltareamehpyfytvvkdqarmg

    Sequence, based on observed residues (ATOM records): (download) 
    >3juhA (A:)
sgpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklgrgkysevfeainitn
nekvavkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfehvnntdf
kqlyqtltdydirfymyeilkaldychsmgimhrdvkphnvlidhehrklrlidwglaef
yhpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnydq
lvriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdfl
dkllrydhqsrltareamehpyfytvvkdqarmg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3juhB (B:)
msgpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklgrgkysevfeainit
nnekvavkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfehvnntd
fkqlyqtltdydirfymyeilkaldychsmgimhrdvkphnvlidhehrklrlidwglae
fyhpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnyd
qlvriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdf
ldkllrydhqsrltareamehpyfytvvkdqarmg

    Sequence, based on observed residues (ATOM records): (download) 
    >3juhB (B:)
sgpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklgrgkysevfeainitn
nekvavkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfehvnntdf
kqlyqtltdydirfymyeilkaldychsmgimhrdvkphnvlidhehrklrlidwglaef
yhpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnydq
lvriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdfl
dkllrydhqsrltareamehpyfytvvkdqarmg