PDB entry 3ixh
View 3ixh on RCSB PDB site
Description: X-ray crystal structure of the extended-spectrum AmpC Y221G mutant beta-lactamase in complex with cefotaxime at 2.3 Angstrom resolution
Class: hydrolase
Keywords: serine hydrolase, beta-lactamase, cephalosporinase, extended-spectrum antibiotic resistance, Antibiotic resistance, Hydrolase
Deposited on
2009-09-04, released
2010-02-16
The last revision prior to the SCOPe 2.04 freeze date was dated
2011-08-24, with a file datestamp of
2011-08-19.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.197
AEROSPACI score: 0.36
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Beta-lactamase
Species: Escherichia coli [TaxId:83333]
Gene: ampA, ampC, b4150, JW4111
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d3ixha_ - Chain 'B':
Compound: Beta-lactamase
Species: Escherichia coli [TaxId:83333]
Gene: ampA, ampC, b4150, JW4111
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d3ixhb_ - Heterogens: PCZ, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>3ixhA (A:)
apqqindivhrtitplieqqkipgmavaviyqgkpyyftwgyadiakkqpvtqqtlfelg
svsktftgvlggdaiargeiklsdpttkywpeltakqwngitllhlatytagglplqvpd
evksssdllrfyqnwqpawapgtqrlyanssiglfgalavkpsglsfeqamqtrvfqplk
lnhtwinvppaeeknyawgyregkavhvspgaldaeaggvkstiedmarwvqsnlkpldi
nektlqqgiqlaqsrywqtgdmyqglgwemldwpvnpdsiingsdnkialaarpvkaitp
ptpavraswvhktgatggfgsyvafipekelgivmlanknypnparvdaawqilnalq
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>3ixhB (B:)
apqqindivhrtitplieqqkipgmavaviyqgkpyyftwgyadiakkqpvtqqtlfelg
svsktftgvlggdaiargeiklsdpttkywpeltakqwngitllhlatytagglplqvpd
evksssdllrfyqnwqpawapgtqrlyanssiglfgalavkpsglsfeqamqtrvfqplk
lnhtwinvppaeeknyawgyregkavhvspgaldaeaggvkstiedmarwvqsnlkpldi
nektlqqgiqlaqsrywqtgdmyqglgwemldwpvnpdsiingsdnkialaarpvkaitp
ptpavraswvhktgatggfgsyvafipekelgivmlanknypnparvdaawqilnalq