PDB entry 3ixg
View 3ixg on RCSB PDB site
Description: X-ray crystal structure of the extended-spectrum AmpC T70I mutant beta-lactamase with and without benzo(b)thiophene-2-boronic acid bound at 2.14 Angstrom resolution
Class: hydrolase
Keywords: serine hydrolase, beta-lactamase, cephalosporinase, extended-spectrum antibiotic resistance, Antibiotic resistance, Hydrolase, Periplasm
Deposited on
2009-09-04, released
2010-02-16
The last revision prior to the SCOPe 2.07 freeze date was dated
2010-02-16, with a file datestamp of
2010-02-12.
Experiment type: XRAY
Resolution: 2.14 Å
R-factor: 0.199
AEROSPACI score: 0.39
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Beta-lactamase
Species: Escherichia coli [TaxId:83333]
Gene: ampA, ampC, b4150, JW4111
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d3ixga_ - Chain 'B':
Compound: Beta-lactamase
Species: Escherichia coli [TaxId:83333]
Gene: ampA, ampC, b4150, JW4111
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d3ixgb_ - Heterogens: BZB, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3ixgA (A:)
apqqindivhrtitplieqqkipgmavaviyqgkpyyftwgyadiakkqpvtqqtlfelg
svsktfigvlggdaiargeiklsdpttkywpeltakqwngitllhlatytagglplqvpd
evksssdllrfyqnwqpawapgtqrlyanssiglfgalavkpsglsfeqamqtrvfqplk
lnhtwinvppaeeknyawgyregkavhvspgaldaeaygvkstiedmarwvqsnlkpldi
nektlqqgiqlaqsrywqtgdmyqglgwemldwpvnpdsiingsdnkialaarpvkaitp
ptpavraswvhktgatggfgsyvafipekelgivmlanknypnparvdaawqilnalq
Sequence, based on observed residues (ATOM records): (download)
>3ixgA (A:)
apqqindivhrtitplieqqkipgmavaviyqgkpyyftwgyadiakkqpvtqqtlfelg
svsktfigvlggdaiargeiklsdpttkywpeltakqwngitllhlatytagglplqvpd
ellrfyqnwqpawapgtqrlyanssiglfgalavkpsglsfeqamqtrvfqplklnhtwi
nvpgvkstiedmarwvqsnlkpldinektlqqgiqlaqsrywqtgdmyqglgwemldwpv
npdsiiialaarpvkaitpptpavraswvhktgatggfgsyvafipekelgivmlankny
pnparvdaawqilnalq
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>3ixgB (B:)
apqqindivhrtitplieqqkipgmavaviyqgkpyyftwgyadiakkqpvtqqtlfelg
svsktfigvlggdaiargeiklsdpttkywpeltakqwngitllhlatytagglplqvpd
evksssdllrfyqnwqpawapgtqrlyanssiglfgalavkpsglsfeqamqtrvfqplk
lnhtwinvppaeeknyawgyregkavhvspgaldaeaygvkstiedmarwvqsnlkpldi
nektlqqgiqlaqsrywqtgdmyqglgwemldwpvnpdsiingsdnkialaarpvkaitp
ptpavraswvhktgatggfgsyvafipekelgivmlanknypnparvdaawqilnalq