PDB entry 3ixa

View 3ixa on RCSB PDB site
Description: Human Class I MHC HLA-A2(A150P) in complex with the Tax peptide
Class: immune system
Keywords: Tel1p, TAX, A150P mutation, nonapeptide, MHC class I, HLA-A2, TCR A6, cross-reactivity, Disulfide bond, Glycoprotein, Host-virus interaction, Immune response, Membrane, MHC I, Phosphoprotein, Transmembrane, Disease mutation, Glycation, Immunoglobulin domain, Pyrrolidone carboxylic acid, Secreted, IMMUNE SYSTEM
Deposited on 2009-09-03, released 2010-01-12
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: HLA class I histocompatibility antigen, A-2 alpha chain
  Species: Homo sapiens [TaxId:9606]
  Gene: HLA-A, HLAA
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01892 (0-274)
    • engineered (149)
• Chain 'B':
  Compound: Beta-2-microglobulin
  Species: Homo sapiens [TaxId:9606]
  Gene: B2M, CDABP0092, HDCMA22P
  Database cross-references and differences (RAF-indexed):
  • Uniprot P61769 (1-99)
    • initiating methionine (0)
  Domains in SCOPe 2.07: d3ixab1, d3ixab2
• Chain 'C':
  Compound: tax peptide
  Species: Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A), synthetic [TaxId:11927]
  Database cross-references and differences (RAF-indexed):
  • PDB 3IXA (0-8)
• Chain 'D':
  Compound: HLA class I histocompatibility antigen, A-2 alpha chain
  Species: Homo sapiens [TaxId:9606]
  Gene: HLA-A, HLAA
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01892 (0-274)
    • engineered (149)
• Chain 'E':
  Compound: Beta-2-microglobulin
  Species: Homo sapiens [TaxId:9606]
  Gene: B2M, CDABP0092, HDCMA22P
  Database cross-references and differences (RAF-indexed):
  • Uniprot P61769 (1-99)
    • initiating methionine (0)
  Domains in SCOPe 2.07: d3ixae1, d3ixae2
• Chain 'F':
  Compound: tax peptide
  Species: Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A), synthetic [TaxId:11927]
  Database cross-references and differences (RAF-indexed):
  • PDB 3IXA (0-8)
• Heterogens: GOL, HOH

PDB Chain Sequences:

• Chain 'A':
  No sequence available.
  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3ixaB (B:)
  miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
  wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
  

  
  
• Chain 'C':
  No sequence available.
  
  
• Chain 'D':
  No sequence available.
  
  
• Chain 'E':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3ixaE (E:)
  miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
  wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
  

  
  
• Chain 'F':
  No sequence available.