PDB entry 3iwi

View 3iwi on RCSB PDB site
Description: X-ray crystal structure of the extended-spectrum AmpC omega loop insertion (H210AAA) mutant beta-lactamase at 1.64 Angstrom resolution
Class: hydrolase
Keywords: serine hydrolase, beta-lactamase, cephalosporinase, extended-spectrum antibiotic resistance, Antibiotic resistance, Hydrolase, Periplasm
Deposited on 2009-09-02, released 2010-02-16
The last revision prior to the SCOPe 2.01 freeze date was dated 2010-02-16, with a file datestamp of 2010-02-12.
Experiment type: XRAY
Resolution: 1.64 Å
R-factor: 0.171
AEROSPACI score: 0.59 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase
    Species: Escherichia coli [TaxId:83333]
    Gene: ampA, ampC, b4150, JW4111
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00811 (0-360)
      • insertion (207-209)
    Domains in SCOPe 2.01: d3iwia_
  • Chain 'B':
    Compound: Beta-lactamase
    Species: Escherichia coli [TaxId:83333]
    Gene: ampA, ampC, b4150, JW4111
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00811 (0-360)
      • insertion (207-209)
    Domains in SCOPe 2.01: d3iwib_
  • Heterogens: PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3iwiA (A:)
    apqqindivhrtitplieqqkipgmavaviyqgkpyyftwgyadiakkqpvtqqtlfelg
    svsktftgvlggdaiargeiklsdpttkywpeltakqwngitllhlatytagglplqvpd
    evksssdllrfyqnwqpawapgtqrlyanssiglfgalavkpsglsfeqamqtrvfqplk
    lnhtwinvppaeeknyawgyregkavhaaavspgaldaeaygvkstiedmarwvqsnlkp
    ldinektlqqgiqlaqsrywqtgdmyqglgwemldwpvnpdsiingsdnkialaarpvka
    itpptpavraswvhktgatggfgsyvafipekelgivmlanknypnparvdaawqilnal
    q
    

    Sequence, based on observed residues (ATOM records): (download)
    >3iwiA (A:)
    apqqindivhrtitplieqqkipgmavaviyqgkpyyftwgyadiakkqpvtqqtlfelg
    svsktftgvlggdaiargeiklsdpttkywpeltakqwngitllhlatytagglplqvpd
    evksssdllrfyqnwqpawapgtqrlyanssiglfgalavkpsglsfeqamqtrvfqplk
    lnhtwinvppaeeknyawgyregkavhaaavspgaldaeaygvkstiedmarwvqsnlkp
    ldinektlqqgiqlaqsrywqtgdmyqglgwemldwpvnpdsiialaarpvkaitpptpa
    vraswvhktgatggfgsyvafipekelgivmlanknypnparvdaawqilnalq
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3iwiB (B:)
    apqqindivhrtitplieqqkipgmavaviyqgkpyyftwgyadiakkqpvtqqtlfelg
    svsktftgvlggdaiargeiklsdpttkywpeltakqwngitllhlatytagglplqvpd
    evksssdllrfyqnwqpawapgtqrlyanssiglfgalavkpsglsfeqamqtrvfqplk
    lnhtwinvppaeeknyawgyregkavhaaavspgaldaeaygvkstiedmarwvqsnlkp
    ldinektlqqgiqlaqsrywqtgdmyqglgwemldwpvnpdsiingsdnkialaarpvka
    itpptpavraswvhktgatggfgsyvafipekelgivmlanknypnparvdaawqilnal
    q