PDB entry 3irt
View 3irt on RCSB PDB site
Description: Crystal Structure of the I93M Mutant of Ubiquitin Carboxy-terminal Hydrolase L1
Class: hydrolase, ligase
Keywords: Ubiquitin Hydrolase, Parkinson's Disease Mutant, Cytoplasm, Disease mutation, Glycoprotein, Hydrolase, Ligase, Oxidation, Polymorphism, Protease, Thiol protease, Ubl conjugation pathway
Deposited on
2009-08-24, released
2010-06-09
The last revision prior to the SCOPe 2.08 freeze date was dated
2010-06-09, with a file datestamp of
2010-06-04.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.213
AEROSPACI score: 0.28
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Ubiquitin carboxyl-terminal hydrolase isozyme L1
Species: Homo sapiens [TaxId:9606]
Gene: PGP9.5, UCHL1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3irta_ - Chain 'B':
Compound: Ubiquitin carboxyl-terminal hydrolase isozyme L1
Species: Homo sapiens [TaxId:9606]
Gene: PGP9.5, UCHL1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3irtb_ - Heterogens: CL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3irtA (A:)
gplgsmqlkpmeinpemlnkvlsrlgvagqwrfvdvlgleeeslgsvpapacallllfpl
taqhenfrkkqieelkgqevspkvyfmkqtignscgtmglihavannqdklgfedgsvlk
qflsetekmspedrakcfekneaiqaahdavaqegqcrvddkvnfhfilfnnvdghlyel
dgrmpfpvnhgassedtllkdaakvcreftereqgevrfsavalckaa
Sequence, based on observed residues (ATOM records): (download)
>3irtA (A:)
mqlkpmeinpemlnkvlsrlgvagqwrfvdvlgleeeslgsvpapacallllfpltaqhe
nfrkkqieelkgqevspkvyfmkqtignscgtmglihavannqdklgfedgsvlkqflse
tekmspedrakcfekneaiqaahdavaqegqcrvddkvnfhfilfnnvdghlyeldgrmp
fpvnhgassedtllkdaakvcreftereqgevrfsavalckaa
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3irtB (B:)
gplgsmqlkpmeinpemlnkvlsrlgvagqwrfvdvlgleeeslgsvpapacallllfpl
taqhenfrkkqieelkgqevspkvyfmkqtignscgtmglihavannqdklgfedgsvlk
qflsetekmspedrakcfekneaiqaahdavaqegqcrvddkvnfhfilfnnvdghlyel
dgrmpfpvnhgassedtllkdaakvcreftereqgevrfsavalckaa
Sequence, based on observed residues (ATOM records): (download)
>3irtB (B:)
mqlkpmeinpemlnkvlsrlgvagqwrfvdvlgleeeslgsvpapacallllfpltaqhe
nfrkkqieelkgqevspkvyfmkqtignscgtmglihavannqdklgfedgsvlkqflse
tekmspedrakcfekneaiqaahdavaqegqcrvddkvnfhfilfnnvdghlyeldgrmp
fpvnhgassedtllkdaakvcreftereqgevrfsavalckaa