PDB entry 3iit

View 3iit on RCSB PDB site
Description: Factor XA in complex with a cis-1,2-diaminocyclohexane derivative
Class: hydrolase
Keywords: GLYCOPROTEIN, HYDROLASE, SERINE PROTEASE, PLASMA, BLOOD COAGULATION FACTOR, PROTEIN INHIBITOR COMPLEX, CALCIUM-BINDING, Blood coagulation, Cleavage on pair of basic residues, Disulfide bond, EGF-like domain, Gamma-carboxyglutamic acid, Hydroxylation, Protease, Secreted, Zymogen
Deposited on 2009-08-03, released 2010-08-04
The last revision prior to the SCOPe 2.06 freeze date was dated 2010-08-04, with a file datestamp of 2010-07-30.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.203
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: activated factor xa heavy chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00742 (0-232)
  Domains in SCOPe 2.06: d3iita_
• Chain 'B':
  Compound: factor x light chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00742 (0-53)
  Domains in SCOPe 2.06: d3iitb_
• Heterogens: CA, D14, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3iitA (A:)
  ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
  qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
  tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
  cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmk
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3iitB (B:)
  trklcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtle