PDB entry 3ig7

View 3ig7 on RCSB PDB site
Description: Novel CDK-5 inhibitors - crystal structure of inhibitor EFP with CDK-2
Class: Transferase
Keywords: PROTEIN KINASE, TRANSFERASE,SERINE/THREONINE PROTEIN KINASE, ATP-BINDING, CELL CYCLE, CELL DIVISION, MITOSIS, 4-AMINOIMIDAZOLE, Kinase, Nucleotide-binding, Phosphoprotein, Polymorphism, Serine/threonine-protein kinase
Deposited on 2009-07-27, released 2009-09-08
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-10-13, with a file datestamp of 2009-10-09.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.209
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CDK2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d3ig7a_
  • Heterogens: EFP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3ig7A (A:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

    Sequence, based on observed residues (ATOM records): (download) 
    >3ig7A (A:)
menfqkvekigegtygvvykarnkltgevvalkkivpstaireisllkelnhpnivklld
vihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdl
kpqnllintegaikladfglaraftlwyrapeillgckyystavdiwslgcifaemvtrr
alfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgr
sllsqmlhydpnkrisakaalahpffqdvtkpvphlrl