PDB entry 3i97

View 3i97 on RCSB PDB site
Description: B1 domain of human Neuropilin-1 bound with small molecule EG00229
Class: signaling protein
Keywords: Neuropilin-1, Drug, VEGF, Angiogenesis, Neuropilin, Alternative splicing, Cell membrane, Developmental protein, Differentiation, Disulfide bond, Glycoprotein, Heparan sulfate, Membrane, Neurogenesis, Phosphoprotein, Polymorphism, Proteoglycan, Receptor, Secreted, Transmembrane, MEMBRANE PROTEIN, SIGNALING PROTEIN
Deposited on 2009-07-10, released 2010-03-02
The last revision prior to the SCOPe 2.06 freeze date was dated 2010-04-28, with a file datestamp of 2010-04-23.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.219
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neuropilin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: NP1-B1, NRP, NRP1, VEGF165R
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3i97a_
  • Chain 'B':
    Compound: Neuropilin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: NP1-B1, NRP, NRP1, VEGF165R
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3i97b_
  • Heterogens: 8DR, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3i97A (A:)
    ghmfkcmealgmesgeihsdqitassqystnwsaersrlnypengwtpgedsyrewiqvd
    lgllrfvtavgtqgaisketkkkyyvktykidvssngedwitikegnkpvlfqgntnptd
    vvvavfpkplitrfvrikpatwetgismrfevygckit
    

    Sequence, based on observed residues (ATOM records): (download)
    >3i97A (A:)
    kcmealgmesgeihsdqitassqystnwsaersrlnypengwtpgedsyrewiqvdlgll
    rfvtavgtqgaisketkkkyyvktykidvssngedwitikegnkpvlfqgntnptdvvva
    vfpkplitrfvrikpatwetgismrfevygckit
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3i97B (B:)
    ghmfkcmealgmesgeihsdqitassqystnwsaersrlnypengwtpgedsyrewiqvd
    lgllrfvtavgtqgaisketkkkyyvktykidvssngedwitikegnkpvlfqgntnptd
    vvvavfpkplitrfvrikpatwetgismrfevygckit
    

    Sequence, based on observed residues (ATOM records): (download)
    >3i97B (B:)
    kcmealgmesgeihsdqitassqystnwsaersrlnypengwtpgedsyrewiqvdlgll
    rfvtavgtqgaisketkkkyyvktykidvssngedwitikegnkpvlfqgntnptdvvva
    vfpkplitrfvrikpatwetgismrfevygckit