PDB entry 3i97
View 3i97 on RCSB PDB site
Description: B1 domain of human Neuropilin-1 bound with small molecule EG00229
Class: signaling protein
Keywords: Neuropilin-1, Drug, VEGF, Angiogenesis, Neuropilin, Alternative splicing, Cell membrane, Developmental protein, Differentiation, Disulfide bond, Glycoprotein, Heparan sulfate, Membrane, Neurogenesis, Phosphoprotein, Polymorphism, Proteoglycan, Receptor, Secreted, Transmembrane, MEMBRANE PROTEIN, SIGNALING PROTEIN
Deposited on
2009-07-10, released
2010-03-02
The last revision prior to the SCOPe 2.03 freeze date was dated
2010-04-28, with a file datestamp of
2010-04-23.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.219
AEROSPACI score: 0.24
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Neuropilin-1
Species: Homo sapiens [TaxId:9606]
Gene: NP1-B1, NRP, NRP1, VEGF165R
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d3i97a_ - Chain 'B':
Compound: Neuropilin-1
Species: Homo sapiens [TaxId:9606]
Gene: NP1-B1, NRP, NRP1, VEGF165R
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d3i97b_ - Heterogens: 8DR, GOL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3i97A (A:)
ghmfkcmealgmesgeihsdqitassqystnwsaersrlnypengwtpgedsyrewiqvd
lgllrfvtavgtqgaisketkkkyyvktykidvssngedwitikegnkpvlfqgntnptd
vvvavfpkplitrfvrikpatwetgismrfevygckit
Sequence, based on observed residues (ATOM records): (download)
>3i97A (A:)
kcmealgmesgeihsdqitassqystnwsaersrlnypengwtpgedsyrewiqvdlgll
rfvtavgtqgaisketkkkyyvktykidvssngedwitikegnkpvlfqgntnptdvvva
vfpkplitrfvrikpatwetgismrfevygckit
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3i97B (B:)
ghmfkcmealgmesgeihsdqitassqystnwsaersrlnypengwtpgedsyrewiqvd
lgllrfvtavgtqgaisketkkkyyvktykidvssngedwitikegnkpvlfqgntnptd
vvvavfpkplitrfvrikpatwetgismrfevygckit
Sequence, based on observed residues (ATOM records): (download)
>3i97B (B:)
kcmealgmesgeihsdqitassqystnwsaersrlnypengwtpgedsyrewiqvdlgll
rfvtavgtqgaisketkkkyyvktykidvssngedwitikegnkpvlfqgntnptdvvva
vfpkplitrfvrikpatwetgismrfevygckit