PDB entry 3i7s

View 3i7s on RCSB PDB site
Description: Dihydrodipicolinate synthase mutant - K161A - with the substrate pyruvate bound in the active site.
Class: lyase
Keywords: dihydrodipicolinate synthyase, lysine biosynthesis, Amino-acid biosynthesis, Diaminopimelate biosynthesis, Lyase, Schiff base
Deposited on 2009-07-08, released 2010-04-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.198
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dihydrodipicolinate synthase
    Species: Escherichia coli K-12 [TaxId:83333]
    Gene: b2478, dapA, JW2463
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6L2 (0-291)
      • engineered (160)
    Domains in SCOPe 2.08: d3i7sa_
  • Chain 'B':
    Compound: Dihydrodipicolinate synthase
    Species: Escherichia coli K-12 [TaxId:83333]
    Gene: b2478, dapA, JW2463
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6L2 (0-291)
      • engineered (160)
    Domains in SCOPe 2.08: d3i7sb_
  • Heterogens: GOL, K, PYR, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3i7sA (A:)
mftgsivaivtpmdekgnvcraslkklidyhvasgtsaivsvgttgesatlnhdehadvv
mmtldladgripviagtganataeaisltqrfndsgivgcltvtpyynrpsqeglyqhfk
aiaehtdlpqilynvpsrtgcdllpetvgrlakvkniigireatgnltrvnqikelvsdd
fvllsgddasaldfmqlgghgvisvtanvaardmaqmcklaaeghfaearvinqrlmplh
nklfvepnpipvkwackelglvatdtlrlpmtpitdsgretvraalkhagll

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3i7sB (B:)
mftgsivaivtpmdekgnvcraslkklidyhvasgtsaivsvgttgesatlnhdehadvv
mmtldladgripviagtganataeaisltqrfndsgivgcltvtpyynrpsqeglyqhfk
aiaehtdlpqilynvpsrtgcdllpetvgrlakvkniigireatgnltrvnqikelvsdd
fvllsgddasaldfmqlgghgvisvtanvaardmaqmcklaaeghfaearvinqrlmplh
nklfvepnpipvkwackelglvatdtlrlpmtpitdsgretvraalkhagll