PDB entry 3hr4

View 3hr4 on RCSB PDB site
Description: Human iNOS Reductase and Calmodulin Complex
Class: Oxidoreductase/METAL BINDING PROTEIN
Keywords: inducible nitric oxide synthase, NOS, iNOS, calmodulin, Calmodulin-binding, FAD, FMN, Heme, Iron, Metal-binding, NADP, Oxidoreductase, Phosphoprotein, Isopeptide bond, Methylation, Oxidoreductase-METAL BINDING PROTEIN COMPLEX
Deposited on 2009-06-08, released 2009-09-08
The last revision prior to the SCOPe 2.05 freeze date was dated 2012-09-05, with a file datestamp of 2012-08-31.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.237
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nitric oxide synthase, inducible
    Species: Homo sapiens [TaxId:9606]
    Gene: Calmodulin, Inducible Nitric Oxide Synthase, NOS2, NOS2A
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: calmodulin
    Species: Homo sapiens [TaxId:9606]
    Gene: CALM1, CALM, CAM, CAM1, CALM2, CAM2, CAMB, CALM3, CALML2, CAM3, CAMC, CAMIII
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3hr4b_
  • Chain 'C':
    Compound: Nitric oxide synthase, inducible
    Species: Homo sapiens [TaxId:9606]
    Gene: Calmodulin, Inducible Nitric Oxide Synthase, NOS2, NOS2A
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: calmodulin
    Species: Homo sapiens [TaxId:9606]
    Gene: CALM1, CALM, CAM, CAM1, CALM2, CAM2, CAMB, CALM3, CALML2, CAM3, CAMC, CAMIII
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3hr4d_
  • Chain 'E':
    Compound: Nitric oxide synthase, inducible
    Species: Homo sapiens [TaxId:9606]
    Gene: Calmodulin, Inducible Nitric Oxide Synthase, NOS2, NOS2A
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: calmodulin
    Species: Homo sapiens [TaxId:9606]
    Gene: CALM1, CALM, CAM, CAM1, CALM2, CAM2, CAMB, CALM3, CALML2, CAM3, CAMC, CAMIII
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3hr4f_
  • Chain 'G':
    Compound: Nitric oxide synthase, inducible
    Species: Homo sapiens [TaxId:9606]
    Gene: Calmodulin, Inducible Nitric Oxide Synthase, NOS2, NOS2A
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: calmodulin
    Species: Homo sapiens [TaxId:9606]
    Gene: CALM1, CALM, CAM, CAM1, CALM2, CAM2, CAMB, CALM3, CALML2, CAM3, CAMC, CAMIII
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3hr4h_
  • Heterogens: FMN, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3hr4B (B:)
madqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadg
ngtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltde
evdemireadidgdgqvnyeefvqmmtak

    Sequence, based on observed residues (ATOM records): (download) 
    >3hr4B (B:)
qlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngt
idfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevd
emireadidgdgqvnyeefvqmmta

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3hr4D (D:)
madqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadg
ngtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltde
evdemireadidgdgqvnyeefvqmmtak

    Sequence, based on observed residues (ATOM records): (download) 
    >3hr4D (D:)
qlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngt
idfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevd
emireadidgdgqvnyeefvqmmta

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >3hr4F (F:)
madqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadg
ngtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltde
evdemireadidgdgqvnyeefvqmmtak

    Sequence, based on observed residues (ATOM records): (download) 
    >3hr4F (F:)
qlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngt
idfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevd
emireadidgdgqvnyeefvqmmta

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >3hr4H (H:)
madqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadg
ngtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltde
evdemireadidgdgqvnyeefvqmmtak

    Sequence, based on observed residues (ATOM records): (download) 
    >3hr4H (H:)
qlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngt
idfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevd
emireadidgdgqvnyeefvqmmta