PDB entry 3hor

View 3hor on RCSB PDB site
Description: Structure of the actin-binding domain of human filamin A (reduced)
Class: Structural Protein
Keywords: Calponin homology domain, actin binding domain, Acetylation, Actin-binding, Alternative splicing, Cytoplasm, Cytoskeleton, Disease mutation, Phosphoprotein, Polymorphism, Structural Protein
Deposited on 2009-06-03, released 2009-10-13
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-12-01, with a file datestamp of 2009-11-27.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.228
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Filamin-A
    Species: Homo sapiens [TaxId:9606]
    Gene: FLNA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3hora1, d3hora2
  • Chain 'B':
    Compound: Filamin-A
    Species: Homo sapiens [TaxId:9606]
    Gene: FLNA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3horb1, d3horb2
  • Heterogens: PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3horA (A:)
    gamassshsragqsaagaapgggvdtrdaempatekdlaedapwkkiqqntftrwcnehl
    kcvskrianlqtdlsdglrliallevlsqkkmhrkhnqrptfrqmqlenvsvalefldre
    siklvsidskaivdgnlklilgliwtlilhysismpmwdeeedeeakkqtpkqrllgwiq
    nklpqlpitnfsrdwqsgralgalvdscapglcpdwdswdaskpvtnareamqqaddwlg
    ipqvitpeeivdpnvdehsvmtylsqfpkakl
    

    Sequence, based on observed residues (ATOM records): (download)
    >3horA (A:)
    kiqqntftrwcnehlkcvskrianlqtdlsdglrliallevlsqkkmhrkhnqrptfrqm
    qlenvsvalefldresiklvsidskaivdgnlklilgliwtlilhysismpqtpkqrllg
    wiqnklpqlpitnfsrdwqsgralgalvdscapglcpdwdswdaskpvtnareamqqadd
    wlgipqvitpeeivdpnvdehsvmtylsqf
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3horB (B:)
    gamassshsragqsaagaapgggvdtrdaempatekdlaedapwkkiqqntftrwcnehl
    kcvskrianlqtdlsdglrliallevlsqkkmhrkhnqrptfrqmqlenvsvalefldre
    siklvsidskaivdgnlklilgliwtlilhysismpmwdeeedeeakkqtpkqrllgwiq
    nklpqlpitnfsrdwqsgralgalvdscapglcpdwdswdaskpvtnareamqqaddwlg
    ipqvitpeeivdpnvdehsvmtylsqfpkakl
    

    Sequence, based on observed residues (ATOM records): (download)
    >3horB (B:)
    iqqntftrwcnehlkcvskrianlqtdlsdglrliallevlsqkkmhrkhnqrptfrqmq
    lenvsvalefldresiklvsidskaivdgnlklilgliwtlilhysismpmwllgwiqnk
    lpqlpitnfsrdwqsgralgalvdscapglcpdwdswdaskpvtnareamqqaddwlgip
    qvitpeeivdpnvdehsvmtylsqfpkakl