PDB entry 3hcv

View 3hcv on RCSB PDB site
Description: Crystal structure of HLA-B*2709 complexed with the double citrullinated vasoactive intestinal peptide type 1 receptor (VIPR) peptide (residues 400-408)
Class: immune system
Keywords: IMMUNE SYSTEM/COMPLEX, MHC (MAJOR HISTOCOMPATIBILITY COMPLEX) I, HLA-B*2709, GLYCOPROTEIN, HOST-VIRUS, IMMUNE RESPONSE, POLYMORPHISM, IMMUNOGLOBULIN DOMAIN, HOST-VIRUS INTERACTION, MEMBRANE, TRANSMEMBRANE, UBL CONJUGATION, DISEASE MUTATION, GLYCATION, PYRROLIDONE CARBOXYLIC ACID, SECRETED, Disulfide bond, MHC I
Deposited on 2009-05-06, released 2009-06-09
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-06-09, with a file datestamp of 2009-06-05.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.201
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, B-27 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-B, HLAB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03989 (0-275)
      • variant (115)
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • initiating methionine (0)
    Domains in SCOPe 2.02: d3hcvb_
  • Chain 'C':
    Compound: double citrullinated vasoactive intestinal polypeptide receptor
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3HCV (0-8)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3hcvB (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    No sequence available.