PDB entry 3h9s

View 3h9s on RCSB PDB site
Description: The complex between TCR A6 and human Class I MHC HLA-A2 with the bound Tel1p peptide
Class: immune system
Keywords: Tel1p peptide, nonapeptide, MHC class I, HLA-A2, TCR A6, cross-reactivity, Disulfide bond, Glycoprotein, Host-virus interaction, Immune response, Membrane, MHC I, Phosphoprotein, Transmembrane, Disease mutation, Glycation, Immunoglobulin domain, Pyrrolidone carboxylic acid, Secreted, IMMUNE SYSTEM
Deposited on 2009-04-30, released 2010-01-12
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.221
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, A-2 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-A, HLAA
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • insertion (0)
    Domains in SCOPe 2.06: d3h9sb1, d3h9sb2
  • Chain 'C':
    Compound: Tel1p peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3H9S (0-8)
  • Chain 'D':
    Compound: A6 TCR alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3H9S (0-199)
  • Chain 'E':
    Compound: TRBV6-5 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: TRBV6-5
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q2YDB4 (0-244)
      • insertion (96-97)
      • conflict (98)
      • conflict (100-102)
      • conflict (112-113)
      • conflict (189)
      • conflict (203)
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3h9sB (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.