PDB entry 3gsr

View 3gsr on RCSB PDB site
Description: Crystal structure of the binary complex between HLA-A2 and HCMV NLV-M5V peptide variant
Class: immune system
Keywords: hla, human cytomegalovirus, pp65, t cell receptor (tcr), immune response, public response, immunodominance,restrained response, host-virus interaction, membrane, MHC I, polymorphism, immunoglobulin domain, immune system
Deposited on 2009-03-27, released 2009-08-04
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-08-04, with a file datestamp of 2009-07-31.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.194
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, A-2 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA, HLA-A, HLAA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01892 (0-273)
      • engineered (244)
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, Beta-2 microglubulin, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • initiating methionine (0)
    Domains in SCOPe 2.02: d3gsrb_
  • Chain 'P':
    Compound: HCMV pp65 fragment 495-503, variant M5V (NLVPVVATV)
    Database cross-references and differences (RAF-indexed):
    • PDB 3GSR (0-8)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3gsrB (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'P':
    No sequence available.