PDB entry 3gcw
View 3gcw on RCSB PDB site
Description: pcsk9:egfa(h306y)
Class: protein binding
Keywords: PCSK9, LDL receptor, Autocatalytic cleavage, Cholesterol metabolism, Disease mutation, Glycoprotein, Hydrolase, Lipid metabolism, Phosphoprotein, Protease, Secreted, Serine protease, Steroid metabolism, Zymogen, Coated pit, EGF-like domain, Endocytosis, Host-virus interaction, LDL, Lipid transport, Membrane, Receptor, Transmembrane, Transport, PROTEIN BINDING
Deposited on
2009-02-22, released
2009-03-03
The last revision prior to the SCOPe 2.05 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-08.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.236
AEROSPACI score: 0.25
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Proprotein convertase subtilisin/kexin type 9
Species: Homo sapiens [TaxId:9606]
Gene: PCSK9, NARC1, PSEC0052
Database cross-references and differences (RAF-indexed):
- Chain 'E':
Compound: low-density lipoprotein receptor
Species: Homo sapiens [TaxId:9606]
Gene: LDLR
Database cross-references and differences (RAF-indexed):
- Uniprot P01130 (3-End)
- expression tag (2)
- engineered (16)
Domains in SCOPe 2.05: d3gcwe_ - Chain 'P':
Compound: Proprotein convertase subtilisin/kexin type 9
Species: Homo sapiens [TaxId:9606]
Gene: PCSK9, NARC1, PSEC0052
Database cross-references and differences (RAF-indexed):
- Heterogens: CA