PDB entry 3gbn

View 3gbn on RCSB PDB site
Description: Crystal Structure of Fab CR6261 in Complex with the 1918 H1N1 influenza virus hemagglutinin
Class: viral protein/immune system
Keywords: hemagglutinin, Fab, neutralizing antibodies, antibody, pandemic flu, Cell membrane, Envelope protein, Fusion protein, Glycoprotein, Lipoprotein, Membrane, Palmitate, Transmembrane, Virion, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
Deposited on 2009-02-20, released 2009-03-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hemagglutinin
    Species: Influenza A virus (A/Brevig Mission/1/1918(H1N1)) [TaxId:88776]
    Gene: HA, Hemagglutinin (HA)
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9WFX3 (4-End)
      • expression tag (0-3)
    Domains in SCOPe 2.08: d3gbna1, d3gbna2
  • Chain 'B':
    Compound: Hemagglutinin
    Species: Influenza A virus (A/Brevig Mission/1/1918(H1N1)) [TaxId:88776]
    Gene: HA, Hemagglutinin (HA)
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3gbnb_
  • Chain 'H':
    Compound: Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3GBN (0-End)
    Domains in SCOPe 2.08: d3gbnh_
  • Chain 'L':
    Compound: Fab Lambda Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3GBN
    Domains in SCOPe 2.08: d3gbnl1
  • Heterogens: NAG, EDO, GOL, ETX, CL, UNL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3gbnA (A:)
adpgdticigyhannstdtvdtvleknvtvthsvnlledshngklcklkgiaplqlgkcn
iagwllgnpecdllltasswsyivetsnsengtcypgdfidyeelreqlssvssfekfei
fpktsswpnhettkgvtaacsyagassfyrnllwltkkgssypklsksyvnnkgkevlvl
wgvhhpptgtdqqslyqnadayvsvgsskynrrftpeiaarpkvrdqagrmnyywtllep
gdtitfeatgnliapwyafalnrgsgsgiitsdapvhdcntkcqtphgainsslpfqnih
pvtigecpkyvrstklrmatglrnipsiqsr

    Sequence, based on observed residues (ATOM records): (download) 
    >3gbnA (A:)
adpgdticigyhannstdtvdtvleknvtvthsvnlledshngklcklkgiaplqlgkcn
iagwllgnpecdllltasswsyivetsnsengtcypgdfidyeelreqlssvssfekfei
fpktsswpnhettkgvtaacsyagassfyrnllwltkkgssypklsksyvnnkgkevlvl
wgvhhpptgtdqqslyqnadayvsvgsskynrrftpeiaarpkvrdqagrmnyywtllep
gdtitfeatgnliapwyafalnrgsgsgiitsdapvhdcntkcqtphgainsslpfqnih
pvtigecpkyvrstklrmatglrnipsi

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3gbnB (B:)
glfgaiagfieggwtgmidgwygyhhqneqgsgyaadqkstqnaidgitnkvnsviekmn
tqftavgkefnnlerrienlnkkvddgfldiwtynaellvllenertldfhdsnvrnlye
kvksqlknnakeigngcfefyhkcddacmesvrngtydypkyseesklnreeidgvsgr

    Sequence, based on observed residues (ATOM records): (download) 
    >3gbnB (B:)
glfgaiagfieggwtgmidgwygyhhqneqgsgyaadqkstqnaidgitnkvnsviekmn
tqftavgkefnnlerrienlnkkvddgfldiwtynaellvllenertldfhdsnvrnlye
kvksqlknnakeigngcfefyhkcddacmesvrngtydypkyseesklnreei

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >3gbnH (H:)
evqlvesgaevkkpgssvkvsckasggpfrsyaiswvrqapgqgpewmggiipifgttky
apkfqgrvtitaddfagtvymelsslrsedtamyycakhmgyqvretmdvwgkgttvtvs
sastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdk

    Sequence, based on observed residues (ATOM records): (download) 
    >3gbnH (H:)
evqlvesgaevkkpgssvkvsckasggpfrsyaiswvrqapgqgpewmggiipifgttky
apkfqgrvtitaddfagtvymelsslrsedtamyycakhmgyqvretmdvwgkgttvtvs
sastkgpsvfplgclvkdyfpepvttfpavlqssglysls

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >3gbnL (L:)
qsvltqppsvsaapgqkvtiscsgsssnigndyvswyqqlpgtapklliydnnkrpsgip
drfsgsksgtsatlgitglqtgdeanyycatwdrrptayvvfgggtkltvlgaaagqpka
apsvtlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnk
yaassylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >3gbnL (L:)
vltqppsvsaapgqkvtiscsgsssnigndyvswyqqlpgtapklliydnnkrpsgipdr
fsgsksgtsatlgitglqtgdeanyycatwdrrptayvvfgggtkltvleelqankatlv
clisdfygvetttpskqsnnkyaassylscq