PDB entry 3g75
View 3g75 on RCSB PDB site
Description: Crystal structure of Staphylococcus aureus Gyrase B co-complexed with 4-METHYL-5-[3-(METHYLSULFANYL)-1H-PYRAZOL-5-YL]-2-THIOPHEN-2-YL-1,3-THIAZOLE inhibitor
Class: Isomerase/Isomerase inhibitor
Keywords: Antibiotic resistance, Isomerase, Isomerase-Isomerase inhibitor complex
Deposited on
2009-02-09, released
2010-02-09
The last revision prior to the SCOPe 2.05 freeze date was dated
2013-07-03, with a file datestamp of
2013-06-28.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.249
AEROSPACI score: 0.3
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: DNA gyrase subunit b
Species: Staphylococcus aureus [TaxId:1280]
Gene: GYRB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d3g75a_ - Chain 'B':
Compound: DNA gyrase subunit b
Species: Staphylococcus aureus [TaxId:1280]
Gene: GYRB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d3g75b_ - Heterogens: B48, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>3g75A (A:)
gleavrkrpgmyigstserglhhlvweivdnsidealagyanqievviekdnwikvtdng
rgipvdiqekmgrpaveviltssvvnalsqdlevyvhrnetiyhqaykkgvpqfdlkevg
ttdktgtvirfkadgeiftettvynyetlqqrirelaflnkgiqitlrderdeenvreds
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- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>3g75B (B:)
gleavrkrpgmyigstserglhhlvweivdnsidealagyanqievviekdnwikvtdng
rgipvdiqekmgrpaveviltssvvnalsqdlevyvhrnetiyhqaykkgvpqfdlkevg
ttdktgtvirfkadgeiftettvynyetlqqrirelaflnkgiqitlrderdeenvreds
yhye