PDB entry 3fvf

View 3fvf on RCSB PDB site
Description: The Crystal Structure of Prostasin Complexed with Camostat at 1.6 Angstroms Resolution
Class: hydrolase
Keywords: PROSTASIN, HCAP-1, CHANNEL ACTIVATING PROTEASE, INHIBITOR, SERINE PROTEASE, ENAC, Cell membrane, Glycoprotein, Hydrolase, Membrane, Protease, Secreted, Transmembrane, Zymogen
Deposited on 2009-01-15, released 2009-05-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'B':
    Compound: Prostasin
    Species: Homo sapiens [TaxId:9606]
    Gene: PRSS8
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q16651 (0-End)
      • engineered (109)
      • engineered (114)
      • engineered (158)
    Domains in SCOPe 2.08: d3fvfb_
  • Heterogens: GOL, 1JZ, DMS, HOH

PDB Chain Sequences:

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3fvfB (B:)
itggssavagqwpwqvsityegvhvcggslvseqwvlsaahcfpsehhkeayevklgahq
ldsysedakvstlkdiiphpsylqegsqgdiallqlsrpitfsryirpislpaaqasfpn
glhctvtgwghvapsvslltpkplqqlevplisretcnslynidakpeephfvqedmvca
gyveggkdacqgdsggplscpveglwyltgivswgdacgarnrpgvytlassyaswiqsk
vtelqprvvpqtqesqpdsnlhhhhhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3fvfB (B:)
itggssavagqwpwqvsityegvhvcggslvseqwvlsaahcfpsehhkeayevklgahq
ldsysedakvstlkdiiphpsylqegsqgdiallqlsrpitfsryirpislpaaqasfpn
glhctvtgwghvapsvslltpkplqqlevplisretcnslynidakpeephfvqedmvca
gyveggkdacqgdsggplscpveglwyltgivswgdacgarnrpgvytlassyaswiqsk
vtelqprv