PDB entry 3fub

View 3fub on RCSB PDB site
Description: Crystal structure of GDNF-GFRalpha1 complex
Class: hormone
Keywords: GFRALPHA1, ALL ALPHA GDNF, CYSTINE KNOT, Cell membrane, Glycoprotein, GPI-anchor, Lipoprotein, Membrane, Receptor, Cleavage on pair of basic residues, Disease mutation, Growth factor, Hirschsprung disease, Secreted, HORMONE
Deposited on 2009-01-14, released 2009-06-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: gdnf family receptor alpha-1
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: glial cell line-derived neurotrophic factor
    Species: Homo sapiens [TaxId:9606]
    Gene: GDNF
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3fubb_
  • Chain 'C':
    Compound: gdnf family receptor alpha-1
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: glial cell line-derived neurotrophic factor
    Species: Homo sapiens [TaxId:9606]
    Gene: GDNF
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3fubd_
  • Heterogens: EDO, NAG, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3fubB (B:)
spdkqmavlprrernrqaaaanpensrgkgrrgqrgknrgcvltaihlnvtdlglgyetk
eelifrycsgscdaaettydkilknlsrnrrlvsdkvgqaccrpiafdddlsflddnlvy
hilrkhsakrcgci

    Sequence, based on observed residues (ATOM records): (download) 
    >3fubB (B:)
gcvltaihlnvtdlglgyetkeelifrycsgscdaaettydkilknlsrnrrlkvgqacc
rpiafdddlsflddnlvyhilrkhsakrcgci

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3fubD (D:)
spdkqmavlprrernrqaaaanpensrgkgrrgqrgknrgcvltaihlnvtdlglgyetk
eelifrycsgscdaaettydkilknlsrnrrlvsdkvgqaccrpiafdddlsflddnlvy
hilrkhsakrcgci

    Sequence, based on observed residues (ATOM records): (download) 
    >3fubD (D:)
rgqrgknrgcvltaihlnvtdlglgyetkeelifrycsgscdaaettydkilknlsrnrr
lvsdkvgqaccrpiafdddlsflddnlvyhilrkhsakrcgci