PDB entry 3fqw

View 3fqw on RCSB PDB site
Description: Phosphorylation of self-peptides alters Human Leukocyte Antigen Class I-restricted antigen presentation and generates tumor specific epitopes
Class: immune system
Keywords: IMMUNE SYSTEM, PHOSPHORYLATION, Glycoprotein, Immune response, Membrane, MHC I, Phosphoprotein, Polymorphism, Transmembrane, Ubl conjugation, Disease mutation, Immunoglobulin domain, Pyrrolidone carboxylic acid, Secreted, cancer, TCR, self-epitope
Deposited on 2009-01-07, released 2009-03-03
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-03-10, with a file datestamp of 2009-03-06.
Experiment type: XRAY
Resolution: 1.93 Å
R-factor: 0.17
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, A-2 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-A, HLAA
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3fqwb_
  • Chain 'C':
    Compound: peptide 1097-1105 from insulin receptor substrate 2 (IRS2): RVASPTSGV
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3FQW (0-8)
  • Heterogens: CD, CO, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3fqwB (B:)
    qrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdws
    fyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    No sequence available.