PDB entry 3fqu

View 3fqu on RCSB PDB site
Description: Phosphorylation of self-peptides alters Human Leukocyte Antigen Class I-restricted antigen presentation and generates tumor specific epitopes
Class: immune system
Keywords: IMMUNE SYSTEM, PHOSPHORYLATION, Glycoprotein, Immune response, Membrane, MHC I, Phosphoprotein, Transmembrane, Disease mutation, Immunoglobulin domain, Pyrrolidone carboxylic acid, Secreted, cancer, TCR, self-epitope
Deposited on 2009-01-07, released 2009-03-03
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: HLA class I histocompatibility antigen, A-2 alpha chain
  Species: Homo sapiens [TaxId:9606]
  Gene: HLA-A, HLAA
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01892 (0-274)
• Chain 'B':
  Compound: Beta-2-microglobulin
  Species: Homo sapiens [TaxId:9606]
  Gene: B2M
  Database cross-references and differences (RAF-indexed):
  • Uniprot P61769 (0-97)
  Domains in SCOPe 2.07: d3fqub_
• Chain 'C':
  Compound: phospho-peptide 38-46 from cell division cycle 25b (CDC25b): GLLG(Sep)PVRA
  Species: synthetic, synthetic
  Database cross-references and differences (RAF-indexed):
  • PDB 3FQU (0-8)
• Heterogens: GOL, CD, MG, HOH

PDB Chain Sequences:

• Chain 'A':
  No sequence available.
  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3fquB (B:)
  qrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdws
  fyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
  

  
  
• Chain 'C':
  No sequence available.