PDB entry 3fmm

View 3fmm on RCSB PDB site
Description: P38 kinase crystal structure in complex with RO6226
Class: signaling protein, transferase
Keywords: P38; MAP KINASE; SERINE/THREONINE KINASE, ATP-binding, Kinase, Nucleotide-binding, Nucleus, Phosphoprotein, Serine/threonine-protein kinase, Transferase, SIGNALING PROTEIN
Deposited on 2008-12-22, released 2009-12-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-24, with a file datestamp of 2019-07-19.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 14
    Species: Homo sapiens [TaxId:9606]
    Gene: CSBP, CSBP1, CSBP2, CSPB1, MAPK14, MXI2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3fmma_
  • Heterogens: XI2, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3fmmA (A:)
mrgshhhhhhgsmsqerptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktgl
rvavkklsrpfqsiihakrtyrelrllkhmkhenviglldvftparsleefndvylvthl
mgadlnnivkcqkltddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkild
fglarhtddemtgyvatrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdh
idqlklilrlvgtpgaellkkissesarnyiqsltqmpkmnfanvfiganplavdllekm
lvldsdkritaaqalahayfaqyhdpddepvadpydqsfesrdllidewksltydevisf
vpppldqeemes

    Sequence, based on observed residues (ATOM records): (download) 
    >3fmmA (A:)
erptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfqsii
hakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqklt
ddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfgltddemtgyvatr
wyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgael
lkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqalaha
yfaqyhdpddepvadpydqsfesrdllidewksltydevisfvppp