PDB entry 3fi3

View 3fi3 on RCSB PDB site
Description: Crystal structure of JNK3 with indazole inhibitor, SR-3737
Class: transferase
Keywords: JNK3, protein-inhibitor complex, Alternative splicing, ATP-binding, Chromosomal rearrangement, Cytoplasm, Epilepsy, Kinase, Nucleotide-binding, Phosphoprotein, Serine/threonine-protein kinase, Transferase
Deposited on 2008-12-10, released 2009-03-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-06-23, with a file datestamp of 2009-06-19.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.187
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 10
    Species: Homo sapiens [TaxId:9606]
    Gene: JNK3, JNK3A, MAPK10, PRKM10
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3fi3a_
  • Heterogens: JK2, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3fi3A (A:)
mskskvdnqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrp
fqnqthakrayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviq
meldhermsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartagtsf
mmtpyvvtryyrapevilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieq
lgtpcpefmkklqptvrnyvenrpkyagltfpklfpdslfpadsehnklkasqardllsk
mlvidpakrisvddalqhpyinvwydpaeveapppqiydkqlderehtieewkeliykev
mnse

    Sequence, based on observed residues (ATOM records): (download) 
    >3fi3A (A:)
dnqfysvevgdstftvlkryqnlkpigivcaaydavldrnvaikklsrpfqnqthakray
relvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldhermsyl
lyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglarvtryyrapevilgmgyk
envdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcpefmkklqptvrnyvenr
pkyagltfpklfpdslfpadsehnklkasqardllskmlvidpakrisvddalqhpyinv
wyppqiydkqlderehtieewkeliykevmns