PDB entry 3fhx

View 3fhx on RCSB PDB site
Description: Crystal structure of D235A mutant of human pyridoxal kinase
Class: transferase
Keywords: beta sheet with alpha helix, ATP complex, metal ion, transferase, ATP-binding, Kinase, Metal-binding, Nucleotide-binding
Deposited on 2008-12-10, released 2008-12-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.212
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pyridoxal kinase
    Species: Homo sapiens [TaxId:9606]
    Gene: C21orf124, C21orf97, PDXK, PKH, PNK
    Database cross-references and differences (RAF-indexed):
    • Uniprot O00764 (Start-311)
      • engineered (234)
    Domains in SCOPe 2.08: d3fhxa_
  • Chain 'B':
    Compound: Pyridoxal kinase
    Species: Homo sapiens [TaxId:9606]
    Gene: C21orf124, C21orf97, PDXK, PKH, PNK
    Database cross-references and differences (RAF-indexed):
    • Uniprot O00764 (Start-311)
      • engineered (234)
    Domains in SCOPe 2.08: d3fhxb_
  • Heterogens: MG, NA, ATP, PXL, SO4, MPD, PLP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3fhxA (A:)
meeecrvlsiqshvirgyvgnraatfplqvlgfeidavnsvqfsnhtgyahwkgqvlnsd
elqelyeglrlnnmnkydyvltgytrdksflamvvdivqelkqqnprlvyvcdpvlgdkw
dgegsmyvpedllpvykekvvpladiitpnqfeaellsgrkihsqeealrvmdmlhsmgp
dtvvitssdlpspqgsnylivlgsqrrrnpagsvvmerirmdirkvdavfvgtgalfaam
llawthkhpnnlkvacektvstlhhvlqrtiqcakaqagegvrpspmqlelrmvqskrdi
edpeivvqatvl

    Sequence, based on observed residues (ATOM records): (download) 
    >3fhxA (A:)
eecrvlsiqshvirgyvgnraatfplqvlgfeidavnsvqfsnhtgyahwkgqvlnsdel
qelyeglrlnnmnkydyvltgytrdksflamvvdivqelkqqnprlvyvcdpvlgdkwdg
egsmyvpedllpvykekvvpladiitpnqfeaellsgrkihsqeealrvmdmlhsmgpdt
vvitssdlpspqgsnylivlgsqrrrnpsvvmerirmdirkvdavfvgtgalfaamllaw
thkhpnnlkvacektvstlhhvlqrtiqcakaqagegvrpspmqlelrmvqskrdiedpe
ivvqatvl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3fhxB (B:)
meeecrvlsiqshvirgyvgnraatfplqvlgfeidavnsvqfsnhtgyahwkgqvlnsd
elqelyeglrlnnmnkydyvltgytrdksflamvvdivqelkqqnprlvyvcdpvlgdkw
dgegsmyvpedllpvykekvvpladiitpnqfeaellsgrkihsqeealrvmdmlhsmgp
dtvvitssdlpspqgsnylivlgsqrrrnpagsvvmerirmdirkvdavfvgtgalfaam
llawthkhpnnlkvacektvstlhhvlqrtiqcakaqagegvrpspmqlelrmvqskrdi
edpeivvqatvl

    Sequence, based on observed residues (ATOM records): (download) 
    >3fhxB (B:)
eecrvlsiqshvirgyvgnraatfplqvlgfeidavnsvqfsnhtgyahwkgqvlnsdel
qelyeglrlnnmnkydyvltgytrdksflamvvdivqelkqqnprlvyvcdpvlgdkwdg
egsmyvpedllpvykekvvpladiitpnqfeaellsgrkihsqeealrvmdmlhsmgpdt
vvitssdlpspqgsnylivlgsqrrrnpagsvvmerirmdirkvdavfvgtgalfaamll
awthkhpnnlkvacektvstlhhvlqrtiqcakaqagegvrpspmqlelrmvqskrdied
peivvqatvl