PDB entry 3ffc

View 3ffc on RCSB PDB site
Description: Crystal Structure of CF34 TCR in complex with HLA-B8/FLR
Class: immune system
Keywords: TCR-peptide-MHC, Glycoprotein, Host-virus interaction, Immune response, Membrane, MHC I, Transmembrane, Disease mutation, Glycation, Immunoglobulin domain, Pyrrolidone carboxylic acid, Secreted, IMMUNE SYSTEM
Deposited on 2008-12-03, released 2009-01-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-11-13, with a file datestamp of 2019-11-08.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: HLA class I histocompatibility antigen, B-8 alpha chain
  Species: Homo sapiens [TaxId:9606]
  Gene: HLA-B, HLAB
  Database cross-references and differences (RAF-indexed):
  • Uniprot P30460 (0-276)
• Chain 'B':
  Compound: Beta-2-microglobulin
  Species: Homo sapiens [TaxId:9606]
  Gene: B2M, CDABP0092, HDCMA22P
  Database cross-references and differences (RAF-indexed):
  • Uniprot P61769 (1-99)
    • initiating methionine (0)
  Domains in SCOPe 2.08: d3ffcb1, d3ffcb2
• Chain 'C':
  Compound: FLRGRAYGL peptide from an EBV protein
  Species: synthetic construct, synthetic [TaxId:32630]
  Database cross-references and differences (RAF-indexed):
  • PDB 3FFC (0-8)
• Chain 'D':
  Compound: CF34 alpha chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 3FFC (0-201)
• Chain 'E':
  Compound: CF34 beta chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 3FFC (0-246)
• Chain 'F':
  Compound: HLA class I histocompatibility antigen, B-8 alpha chain
  Species: Homo sapiens [TaxId:9606]
  Gene: HLA-B, HLAB
  Database cross-references and differences (RAF-indexed):
  • Uniprot P30460 (0-End)
• Chain 'G':
  Compound: Beta-2-microglobulin
  Species: Homo sapiens [TaxId:9606]
  Gene: B2M, CDABP0092, HDCMA22P
  Database cross-references and differences (RAF-indexed):
  • Uniprot P61769 (1-99)
    • initiating methionine (0)
  Domains in SCOPe 2.08: d3ffcg1, d3ffcg2
• Chain 'H':
  Compound: FLRGRAYGL peptide from an EBV protein
  Species: synthetic construct, synthetic [TaxId:32630]
  Database cross-references and differences (RAF-indexed):
  • PDB 3FFC (0-8)
• Chain 'I':
  Compound: CF34 alpha chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 3FFC (0-201)
• Chain 'J':
  Compound: CF34 beta chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 3FFC (0-246)
• Heterogens: CD, CL, NA, HOH

PDB Chain Sequences:

• Chain 'A':
  No sequence available.
  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3ffcB (B:)
  miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
  wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
  

  
  
• Chain 'C':
  No sequence available.
  
  
• Chain 'D':
  No sequence available.
  
  
• Chain 'E':
  No sequence available.
  
  
• Chain 'F':
  No sequence available.
  
  
• Chain 'G':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3ffcG (G:)
  miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
  wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
  

  
  
• Chain 'H':
  No sequence available.
  
  
• Chain 'I':
  No sequence available.
  
  
• Chain 'J':
  No sequence available.