PDB entry 3eo0
View 3eo0 on RCSB PDB site
Description: Structure of the Transforming Growth Factor-Beta Neutralizing Antibody GC-1008
Class: immune system
Keywords: Cytokine neutralizing antibody, FAB fragment, IMMUNE SYSTEM
Deposited on
2008-09-26, released
2008-12-02
The last revision prior to the SCOPe 2.06 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-25.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.183
AEROSPACI score: 0.53
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: GC-1008 Fab Light Chain
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3eo0a1, d3eo0a2 - Chain 'B':
Compound: GC-1008 Fab Heavy Chain
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
- Chain 'C':
Compound: GC-1008 Fab Light Chain
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3eo0c1, d3eo0c2 - Chain 'D':
Compound: GC-1008 Fab Heavy Chain
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
- Heterogens: GOL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>3eo0A (A:)
etvltqspgtlslspgeratlscrasqslgssylawyqqkpgqaprlliygassrapgip
drfsgsgsgtdftltisrlepedfavyycqqyadspitfgqgtrleikrtvaapsvfifp
psdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstl
tlskadyekhkvyacevthqglsspvtksfnrgec
- Chain 'B':
No sequence available.
- Chain 'C':
Sequence; same for both SEQRES and ATOM records: (download)
>3eo0C (C:)
etvltqspgtlslspgeratlscrasqslgssylawyqqkpgqaprlliygassrapgip
drfsgsgsgtdftltisrlepedfavyycqqyadspitfgqgtrleikrtvaapsvfifp
psdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstl
tlskadyekhkvyacevthqglsspvtksfnrgec
- Chain 'D':
No sequence available.