PDB entry 3ehb

View 3ehb on RCSB PDB site
Description: A D-Pathway Mutation Decouples the Paracoccus Denitrificans Cytochrome c Oxidase by Altering the side chain orientation of a distant, conserved Glutamate
Class: oxidoreductase/immune system
Keywords: proton pumping, water chain, electron transfer, Cell inner membrane, Cell membrane, Copper, Electron transport, Heme, Hydrogen ion transport, Ion transport, Iron, Membrane, Metal-binding, Oxidoreductase, Respiratory chain, Transmembrane, Transport, Pyrrolidone carboxylic acid, OXIDOREDUCTASE/IMMUNE SYSTEM COMPLEX
Deposited on 2008-09-12, released 2008-09-30
The last revision prior to the SCOPe 2.01 freeze date was dated 2008-12-09, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.32 Å
R-factor: 0.206
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytochrome c oxidase subunit 1-beta
    Species: Paracoccus denitrificans [TaxId:266]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P98002
      • engineered (130)
    Domains in SCOPe 2.01: d3ehba_
  • Chain 'B':
    Compound: Cytochrome c oxidase subunit 2
    Species: Paracoccus denitrificans [TaxId:266]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3ehbb1, d3ehbb2
  • Chain 'C':
    Compound: FV fragment Chain H
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 3EHB (0-End)
    Domains in SCOPe 2.01: d3ehbc_
  • Chain 'D':
    Compound: FV fragment Chain L
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 3EHB (0-End)
    Domains in SCOPe 2.01: d3ehbd_
  • Heterogens: HEA, CU, MG, CA, LDA, LMT, PER, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3ehbA (A:)
    madaavhghgdhhdtrgfftrwfmstnhkdigilylftagivglisvcftvymrmelqhp
    gvqymclegarliadasaectpnghlwnvmityhgvlmmffvvipalfggfgnyfmplhi
    gapdmafprldnlsywmyvcgvalgvasllapggndqmgsgvgwvlypplstteagysmd
    laifavhvsgassilgainiittflnmrapgmtlfkvplfawsvfitawlillslpvlag
    aitmllmdrnfgtqffdpagggdpvlyqhilwffghpevyiiilpgfgiishvistfakk
    pifgylpmvlamaaigilgfvvwahhmytagmsltqqayfmlatmtiavptgikvfswia
    tmwggsiefktpmlwafgflflftvggvtgvvlsqapldrvyhdtyyvvahfhyvmslga
    vfgifagvyywigkmsgrqypewagqlhfwmmfigsnliffpqhflgrqgmprryidypv
    efaywnnissigayisfasflffigivfytlfagkrvnvpnywnehadtlewtlpspppe
    htfetlpkredwdrahah
    

    Sequence, based on observed residues (ATOM records): (download)
    >3ehbA (A:)
    gfftrwfmstnhkdigilylftagivglisvcftvymrmelqhpgvqymclegarliada
    saectpnghlwnvmityhgvlmmffvvipalfggfgnyfmplhigapdmafprldnlsyw
    myvcgvalgvasllapggndqmgsgvgwvlypplstteagysmdlaifavhvsgassilg
    ainiittflnmrapgmtlfkvplfawsvfitawlillslpvlagaitmllmdrnfgtqff
    dpagggdpvlyqhilwffghpevyiiilpgfgiishvistfakkpifgylpmvlamaaig
    ilgfvvwahhmytagmsltqqayfmlatmtiavptgikvfswiatmwggsiefktpmlwa
    fgflflftvggvtgvvlsqapldrvyhdtyyvvahfhyvmslgavfgifagvyywigkms
    grqypewagqlhfwmmfigsnliffpqhflgrqgmprryidypvefaywnnissigayis
    fasflffigivfytlfagkrvnvpnywnehadtlewtlpspppehtfetl
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3ehbB (B:)
    mmaiatkrrgvaavmslgvatmtavpalaqdvlgdlpvigkpvnggmnfqpassplahdq
    qwldhfvlyiitavtifvcllllicivrfnrranpvparfthntpieviwtlvpvlilva
    igafslpilfrsqempndpdlvikaighqwywsyeypndgvafdalmlekealadagyse
    deyllatdnpvvvpvgkkvlvqvtatdvihawtipafavkqdavpgriaqlwfsvdqegv
    yfgqcselcginhaympivvkavsqekyeawlagakeefaadasdylpaspvklasae
    

    Sequence, based on observed residues (ATOM records): (download)
    >3ehbB (B:)
    qdvlgdlpvigkpvnggmnfqpassplahdqqwldhfvlyiitavtifvcllllicivrf
    nrranpvparfthntpieviwtlvpvlilvaigafslpilfrsqempndpdlvikaighq
    wywsyeypndgvafdalmlekealadagysedeyllatdnpvvvpvgkkvlvqvtatdvi
    hawtipafavkqdavpgriaqlwfsvdqegvyfgqcselcginhaympivvkavsqekye
    awlagakeefaad
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >3ehbC (C:)
    evklqesggdlvqpggslklscaasgftfssytmswvrqtpekrlewvasinngggrtyy
    pdtvkgrftisrdnakntlylqmsslksedtamyycvrheyyyamdywgqgttvtvssaw
    rhpqfgg
    

    Sequence, based on observed residues (ATOM records): (download)
    >3ehbC (C:)
    evklqesggdlvqpggslklscaasgftfssytmswvrqtpekrlewvasinngggrtyy
    pdtvkgrftisrdnakntlylqmsslksedtamyycvrheyyyamdywgqgttvtvssa
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >3ehbD (D:)
    dieltqtpvslsasvgetvtitcraseniysylawyqqkqgkspqflvynaktlgegvps
    rfsgsgsgtqfslkinsllpedfgsyycqhhygtppltfgggtkleikreqkliseedlm
    

    Sequence, based on observed residues (ATOM records): (download)
    >3ehbD (D:)
    dieltqtpvslsasvgetvtitcraseniysylawyqqkqgkspqflvynaktlgegvps
    rfsgsgsgtqfslkinsllpedfgsyycqhhygtppltfgggtkleikr