PDB entry 3eej

View 3eej on RCSB PDB site
Description: Candida glabrata Dihydrofolate Reductase complexed with 2,4-diamino-5-[3-methyl-3-(3-methoxy-5-phenylphenyl)prop-1-ynyl]-6-methylpyrimidine(UCP111D) and NADPH
Class: oxidoreductase
Keywords: enzyme, OXIDOREDUCTASE
Deposited on 2008-09-04, released 2009-08-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 2.11 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydrofolate reductase
    Species: Candida glabrata [TaxId:5478]
    Gene: CAGL0J03894g
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6FPH0 (Start-216)
      • expression tag (217-226)
    Domains in SCOPe 2.08: d3eeja1, d3eeja2
  • Chain 'B':
    Compound: dihydrofolate reductase
    Species: Candida glabrata [TaxId:5478]
    Gene: CAGL0J03894g
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6FPH0 (Start-216)
      • expression tag (217-226)
    Domains in SCOPe 2.08: d3eejb1, d3eejb2
  • Heterogens: NDP, 53R, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3eejA (A:)
mskvpvvgivaallpemgigfqgnlpwrlakemkyfrevttltndnskqnvvimgrktwe
sipqkfrplpkrinvvvsrsfdgelrkvedgiyhsnslrncltalqsslanenkieriyi
igggeiyrqsmdladhwlitkimplpettipqmdtflqkqeleqrfydnsdklvdflpss
iqlegrltsqewngelvkglpvqekgyqfyftlytkklehhhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3eejA (A:)
kvpvvgivaallpemgigfqgnlpwrlakemkyfrevttltndnskqnvvimgrktwesi
pqkfrplpkrinvvvsrsfdgelrkvedgiyhsnslrncltalqsslanenkieriyiig
ggeiyrqsmdladhwlitkimplpettipqmdtflqkqeleqrfydnsdklvdflpssiq
legrltsqewngelvkglpvqekgyqfyftlytkklehhhhhhhh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3eejB (B:)
mskvpvvgivaallpemgigfqgnlpwrlakemkyfrevttltndnskqnvvimgrktwe
sipqkfrplpkrinvvvsrsfdgelrkvedgiyhsnslrncltalqsslanenkieriyi
igggeiyrqsmdladhwlitkimplpettipqmdtflqkqeleqrfydnsdklvdflpss
iqlegrltsqewngelvkglpvqekgyqfyftlytkklehhhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3eejB (B:)
kvpvvgivaallpemgigfqgnlpwrlakemkyfrevttltndnskqnvvimgrktwesi
pqkfrplpkrinvvvsrsfdgelrkvedgiyhsnslrncltalqsslanenkieriyiig
ggeiyrqsmdladhwlitkimplpettipqmdtflqkqeleqrfydnsdklvdflpssiq
legrltsqewngelvkglpvqekgyqfyftlytkklehhhhhhhh