PDB entry 3ee2
View 3ee2 on RCSB PDB site
Description: Structure of human prostaglandin D-synthase (hGSTS1-1) in complex with nocodazole
Class: isomerase
Keywords: H-PGDS, prostanoid production, inflamation, nocodazole, glutathione transferase sigma, Fatty acid biosynthesis, Isomerase, Lipid synthesis, Prostaglandin biosynthesis
Deposited on
2008-09-04, released
2008-09-16
The last revision prior to the SCOPe 2.06 freeze date was dated
2011-12-14, with a file datestamp of
2011-12-09.
Experiment type: XRAY
Resolution: 1.91 Å
R-factor: 0.186
AEROSPACI score: 0.4
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: glutathione-requiring prostaglandin d synthase
Species: Homo sapiens [TaxId:9606]
Gene: PGDS
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3ee2a1, d3ee2a2 - Chain 'B':
Compound: glutathione-requiring prostaglandin d synthase
Species: Homo sapiens [TaxId:9606]
Gene: PGDS
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3ee2b1, d3ee2b2 - Heterogens: GSH, NZO, MG, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3ee2A (A:)
mpnykltyfnmrgraeiiryifayldiqyedhrieqadwpeikstlpfgkipilevdglt
lhqslaiaryltkntdlagntemeqchvdaivdtlddfmscfpwaekkqdvkeqmfnell
tynaphlmqdldtylggrewlignsvtwadfyweicsttllvfkpdlldnhprlvtlrkk
vqaipaianwikrrpqtkl
Sequence, based on observed residues (ATOM records): (download)
>3ee2A (A:)
pnykltyfnmrgraeiiryifayldiqyedhrieqadwpeikstlpfgkipilevdgltl
hqslaiaryltkntdlagntemeqchvdaivdtlddfmscfpwaekkqdvkeqmfnellt
ynaphlmqdldtylggrewlignsvtwadfyweicsttllvfkpdlldnhprlvtlrkkv
qaipaianwikrrpqtkl
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3ee2B (B:)
mpnykltyfnmrgraeiiryifayldiqyedhrieqadwpeikstlpfgkipilevdglt
lhqslaiaryltkntdlagntemeqchvdaivdtlddfmscfpwaekkqdvkeqmfnell
tynaphlmqdldtylggrewlignsvtwadfyweicsttllvfkpdlldnhprlvtlrkk
vqaipaianwikrrpqtkl
Sequence, based on observed residues (ATOM records): (download)
>3ee2B (B:)
pnykltyfnmrgraeiiryifayldiqyedhrieqadwpeikstlpfgkipilevdgltl
hqslaiaryltkntdlagntemeqchvdaivdtlddfmscfpwaekkqdvkeqmfnellt
ynaphlmqdldtylggrewlignsvtwadfyweicsttllvfkpdlldnhprlvtlrkkv
qaipaianwikrrpqtkl