PDB entry 3e3q

View 3e3q on RCSB PDB site
Description: Structure of the 3alpham13 high-affinity mutant of the 2C TCR in complex with Ld/QL9
Class: immune system
Keywords: TCR, MHC, high affinity, cross reactivity, Glycoprotein, Immune response, Membrane, MHC I, Phosphoprotein, Transmembrane, Immunoglobulin domain, Receptor, IMMUNE SYSTEM
Deposited on 2008-08-07, released 2008-11-04
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.95 Å
R-factor: 0.25
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: H-2 class I histocompatibility antigen, L-D alpha chain
  Species: Mus musculus [TaxId:10090]
  Gene: H2-L
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01897 (0-174)
    • engineered (7)
    • engineered (11)
    • engineered (14)
    • engineered (22)
    • engineered (29)
    • engineered (48)
    • engineered (65)
    • engineered (96)
    • engineered (130)
• Chain 'B':
  Compound: H-2 class I histocompatibility antigen, L-D alpha chain
  Species: Mus musculus [TaxId:10090]
  Gene: H2-L
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01897 (0-174)
    • engineered (7)
    • engineered (11)
    • engineered (14)
    • engineered (22)
    • engineered (29)
    • engineered (48)
    • engineered (65)
    • engineered (96)
    • engineered (130)
• Chain 'C':
  Compound: T-cell receptor alpha chain V region PHDS58
  Species: Mus musculus [TaxId:10090]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01738 (0-108)
    • engineered (41)
    • engineered (80)
    • engineered (92-96)
  Domains in SCOPe 2.06: d3e3qc_
• Chain 'D':
  Compound: T-cell receptor alpha chain V region PHDS58
  Species: Mus musculus [TaxId:10090]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01738 (0-108)
    • engineered (41)
    • engineered (80)
    • engineered (92-96)
• Chain 'E':
  Compound: TCR beta chain
  Species: Mus musculus [TaxId:10090]
  Database cross-references and differences (RAF-indexed):
  • PDB 3E3Q (0-110)
  Domains in SCOPe 2.06: d3e3qe_
• Chain 'F':
  Compound: TCR beta chain
  Species: Mus musculus [TaxId:10090]
  Database cross-references and differences (RAF-indexed):
  • PDB 3E3Q (0-110)
  Domains in SCOPe 2.06: d3e3qf_
• Chain 'G':
  Compound: QL9 peptide
  Species: synthetic, synthetic
  Database cross-references and differences (RAF-indexed):
  • PDB 3E3Q (0-8)
• Chain 'H':
  Compound: H-2 class I histocompatibility antigen, L-D alpha chain
  Species: Mus musculus [TaxId:10090]
  Gene: H2-L
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01897 (0-174)
    • engineered (7)
    • engineered (11)
    • engineered (14)
    • engineered (22)
    • engineered (29)
    • engineered (48)
    • engineered (65)
    • engineered (96)
    • engineered (130)
• Chain 'I':
  Compound: T-cell receptor alpha chain V region PHDS58
  Species: Mus musculus [TaxId:10090]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01738 (0-108)
    • engineered (41)
    • engineered (80)
    • engineered (92-96)
• Chain 'J':
  Compound: TCR beta chain
  Species: Mus musculus [TaxId:10090]
  Database cross-references and differences (RAF-indexed):
  • PDB 3E3Q (0-110)
  Domains in SCOPe 2.06: d3e3qj_
• Chain 'K':
  Compound: QL9 peptide
  Species: synthetic, synthetic
  Database cross-references and differences (RAF-indexed):
  • PDB 3E3Q (0-8)
• Chain 'L':
  Compound: H-2 class I histocompatibility antigen, L-D alpha chain
  Species: Mus musculus [TaxId:10090]
  Gene: H2-L
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01897 (0-174)
    • engineered (7)
    • engineered (11)
    • engineered (14)
    • engineered (22)
    • engineered (29)
    • engineered (48)
    • engineered (65)
    • engineered (96)
    • engineered (130)
• Chain 'M':
  Compound: T-cell receptor alpha chain V region PHDS58
  Species: Mus musculus [TaxId:10090]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01738 (0-108)
    • engineered (41)
    • engineered (80)
    • engineered (92-96)
• Chain 'N':
  Compound: TCR beta chain
  Species: Mus musculus [TaxId:10090]
  Database cross-references and differences (RAF-indexed):
  • PDB 3E3Q (0-110)
  Domains in SCOPe 2.06: d3e3qn_
• Chain 'O':
  Compound: QL9 peptide
  Species: synthetic, synthetic
  Database cross-references and differences (RAF-indexed):
  • PDB 3E3Q (0-8)
• Chain 'P':
  Compound: H-2 class I histocompatibility antigen, L-D alpha chain
  Species: Mus musculus [TaxId:10090]
  Gene: H2-L
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01897 (0-174)
    • engineered (7)
    • engineered (11)
    • engineered (14)
    • engineered (22)
    • engineered (29)
    • engineered (48)
    • engineered (65)
    • engineered (96)
    • engineered (130)
• Chain 'Q':
  Compound: QL9 peptide
  Species: synthetic, synthetic
  Database cross-references and differences (RAF-indexed):
  • PDB 3E3Q (0-8)
• Chain 'R':
  Compound: T-cell receptor alpha chain V region PHDS58
  Species: Mus musculus [TaxId:10090]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01738 (0-108)
    • engineered (41)
    • engineered (80)
    • engineered (92-96)
• Chain 'S':
  Compound: TCR beta chain
  Species: Mus musculus [TaxId:10090]
  Database cross-references and differences (RAF-indexed):
  • PDB 3E3Q (0-110)
  Domains in SCOPe 2.06: d3e3qs_
• Chain 'T':
  Compound: QL9 peptide
  Species: synthetic, synthetic
  Database cross-references and differences (RAF-indexed):
  • PDB 3E3Q (0-8)
• Chain 'U':
  Compound: H-2 class I histocompatibility antigen, L-D alpha chain
  Species: Mus musculus [TaxId:10090]
  Gene: H2-L
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01897 (0-174)
    • engineered (7)
    • engineered (11)
    • engineered (14)
    • engineered (22)
    • engineered (29)
    • engineered (48)
    • engineered (65)
    • engineered (96)
    • engineered (130)
• Chain 'V':
  Compound: T-cell receptor alpha chain V region PHDS58
  Species: Mus musculus [TaxId:10090]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01738 (0-108)
    • engineered (41)
    • engineered (80)
    • engineered (92-96)
• Chain 'W':
  Compound: TCR beta chain
  Species: Mus musculus [TaxId:10090]
  Database cross-references and differences (RAF-indexed):
  • PDB 3E3Q (0-110)
  Domains in SCOPe 2.06: d3e3qw_
• Chain 'X':
  Compound: QL9 peptide
  Species: synthetic, synthetic
  Database cross-references and differences (RAF-indexed):
  • PDB 3E3Q (0-8)
• Chain 'Y':
  Compound: H-2 class I histocompatibility antigen, L-D alpha chain
  Species: Mus musculus [TaxId:10090]
  Gene: H2-L
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01897 (0-174)
    • engineered (7)
    • engineered (11)
    • engineered (14)
    • engineered (22)
    • engineered (29)
    • engineered (48)
    • engineered (65)
    • engineered (96)
    • engineered (130)
• Chain 'Z':
  Compound: T-cell receptor alpha chain V region PHDS58
  Species: Mus musculus [TaxId:10090]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01738 (0-108)
    • engineered (41)
    • engineered (80)
    • engineered (92-96)
• Chain 'a':
  Compound: TCR beta chain
  Species: Mus musculus [TaxId:10090]
  Database cross-references and differences (RAF-indexed):
  • PDB 3E3Q (0-110)
  Domains in SCOPe 2.06: d3e3qa_
• Chain 'b':
  Compound: QL9 peptide
  Species: synthetic, synthetic
  Database cross-references and differences (RAF-indexed):
  • PDB 3E3Q (0-8)
• Chain 'c':
  Compound: H-2 class I histocompatibility antigen, L-D alpha chain
  Species: Mus musculus [TaxId:10090]
  Gene: H2-L
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01897 (0-174)
    • engineered (7)
    • engineered (11)
    • engineered (14)
    • engineered (22)
    • engineered (29)
    • engineered (48)
    • engineered (65)
    • engineered (96)
    • engineered (130)
• Chain 'd':
  Compound: T-cell receptor alpha chain V region PHDS58
  Species: Mus musculus [TaxId:10090]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01738 (0-108)
    • engineered (41)
    • engineered (80)
    • engineered (92-96)
• Chain 'e':
  Compound: TCR beta chain
  Species: Mus musculus [TaxId:10090]
  Database cross-references and differences (RAF-indexed):
  • PDB 3E3Q (0-110)
• Chain 'f':
  Compound: QL9 peptide
  Species: synthetic, synthetic
  Database cross-references and differences (RAF-indexed):
  • PDB 3E3Q (0-8)

PDB Chain Sequences:

• Chain 'A':
  No sequence available.
  
  
• Chain 'B':
  No sequence available.
  
  
• Chain 'C':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3e3qC (C:)
  svtqpdarvtvsegaslqlrckysysatpylfwyvqyprqgpqlllkyysgdpvvqgvng
  feaefsksnssfhlrkasvhrsdsavyfcavsdppplltfgsgtkvivl
  

  
  
• Chain 'D':
  No sequence available.
  
  
• Chain 'E':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3e3qE (E:)
  eaavtqsprnkvavtgekvtlscnqtnnhnnmywyrqdtghelrliyysygagstekgdi
  pdgykasrpsqenfsltlesatpsqtsvyfcasggggtlyfgagtrlsvls
  

  
  
• Chain 'F':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3e3qF (F:)
  eaavtqsprnkvavtgekvtlscnqtnnhnnmywyrqdtghelrliyysygagstekgdi
  pdgykasrpsqenfsltlesatpsqtsvyfcasggggtlyfgagtrlsvls
  

  
  
• Chain 'G':
  No sequence available.
  
  
• Chain 'H':
  No sequence available.
  
  
• Chain 'I':
  No sequence available.
  
  
• Chain 'J':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3e3qJ (J:)
  eaavtqsprnkvavtgekvtlscnqtnnhnnmywyrqdtghelrliyysygagstekgdi
  pdgykasrpsqenfsltlesatpsqtsvyfcasggggtlyfgagtrlsvls
  

  
  
• Chain 'K':
  No sequence available.
  
  
• Chain 'L':
  No sequence available.
  
  
• Chain 'M':
  No sequence available.
  
  
• Chain 'N':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3e3qN (N:)
  eaavtqsprnkvavtgekvtlscnqtnnhnnmywyrqdtghelrliyysygagstekgdi
  pdgykasrpsqenfsltlesatpsqtsvyfcasggggtlyfgagtrlsvls
  

  
  
• Chain 'O':
  No sequence available.
  
  
• Chain 'P':
  No sequence available.
  
  
• Chain 'Q':
  No sequence available.
  
  
• Chain 'R':
  No sequence available.
  
  
• Chain 'S':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3e3qS (S:)
  eaavtqsprnkvavtgekvtlscnqtnnhnnmywyrqdtghelrliyysygagstekgdi
  pdgykasrpsqenfsltlesatpsqtsvyfcasggggtlyfgagtrlsvls
  

  
  
• Chain 'T':
  No sequence available.
  
  
• Chain 'U':
  No sequence available.
  
  
• Chain 'V':
  No sequence available.
  
  
• Chain 'W':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3e3qW (W:)
  eaavtqsprnkvavtgekvtlscnqtnnhnnmywyrqdtghelrliyysygagstekgdi
  pdgykasrpsqenfsltlesatpsqtsvyfcasggggtlyfgagtrlsvls
  

  
  
• Chain 'X':
  No sequence available.
  
  
• Chain 'Y':
  No sequence available.
  
  
• Chain 'Z':
  No sequence available.
  
  
• Chain 'a':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3e3qa (a:)
  eaavtqsprnkvavtgekvtlscnqtnnhnnmywyrqdtghelrliyysygagstekgdi
  pdgykasrpsqenfsltlesatpsqtsvyfcasggggtlyfgagtrlsvls
  

  
  
• Chain 'b':
  No sequence available.
  
  
• Chain 'c':
  No sequence available.
  
  
• Chain 'd':
  No sequence available.
  
  
• Chain 'e':
  No sequence available.
  
  
• Chain 'f':
  No sequence available.