PDB entry 3e2m
View 3e2m on RCSB PDB site
Description: LFA-1 I domain bound to inhibitors
Class: cell adhesion
Keywords: integrin I-domain, leukocyte function associated antigen-1, alternative splicing, calcium, cell adhesion, glycoprotein, magnesium, membrane, polymorphism, receptor, transmembrane
Deposited on
2008-08-05, released
2008-08-19
The last revision prior to the SCOP 1.75 freeze date was dated
2008-10-07, with a file datestamp of
2008-10-03.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.219
AEROSPACI score: 0.5
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Integrin alpha-L
Species: HOMO SAPIENS
Gene: ITGAL, CD11A
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d3e2ma1 - Chain 'B':
Compound: Integrin alpha-L
Species: HOMO SAPIENS
Gene: ITGAL, CD11A
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d3e2mb1 - Heterogens: E2M, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3e2mA (A:)
gskgnvdlvflfdgsmslqpdefqkildfmkdvmkklsntsyqfaavqfstsyktefdfs
dyvkwkdpdallkhvkhmllltntfgainyvatevfreelgarpdatkvliiitdgeatd
sgnidaakdiiryiigigkhfqtkesqetlhkfaskpasefvkildtfeklkdlftelqk
kiyvi
Sequence, based on observed residues (ATOM records): (download)
>3e2mA (A:)
gnvdlvflfdgsmslqpdefqkildfmkdvmkklsntsyqfaavqfstsyktefdfsdyv
kwkdpdallkhvkhmllltntfgainyvatevfreelgarpdatkvliiitdgeatdsgn
idaakdiiryiigigkhfqtkesqetlhkfaskpasefvkildtfeklkdlftelqkkiy
vi
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3e2mB (B:)
gskgnvdlvflfdgsmslqpdefqkildfmkdvmkklsntsyqfaavqfstsyktefdfs
dyvkwkdpdallkhvkhmllltntfgainyvatevfreelgarpdatkvliiitdgeatd
sgnidaakdiiryiigigkhfqtkesqetlhkfaskpasefvkildtfeklkdlftelqk
kiyvi
Sequence, based on observed residues (ATOM records): (download)
>3e2mB (B:)
gnvdlvflfdgsmslqpdefqkildfmkdvmkklsntsyqfaavqfstsyktefdfsdyv
kwkdpdallkhvkhmllltntfgainyvatevfreelgarpdatkvliiitdgeatdsgn
idaakdiiryiigigkhfqtkesqetlhkfaskpasefvkildtfeklkdlftelqkkiy
vi