PDB entry 3dvg

View 3dvg on RCSB PDB site
Description: Crystal structure of K63-specific fab Apu.3A8 bound to K63-linked di-ubiquitin
Class: immune system
Keywords: di-ubiquitin, fab fragment, antibody, Nucleus, Phosphoprotein, Ribosomal protein, IMMUNE SYSTEM
Deposited on 2008-07-18, released 2008-09-30
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.224
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Human IgG1 fab fragment light chain
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Gene: fab fragment light chain
    Database cross-references and differences (RAF-indexed):
    • PDB 3DVG
    Domains in SCOPe 2.01: d3dvga1, d3dvga2
  • Chain 'B':
    Compound: Human IgG1 fab fragment heavy chain
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Gene: fab fragment light chain
    Database cross-references and differences (RAF-indexed):
    • PDB 3DVG
    Domains in SCOPe 2.01: d3dvgb1, d3dvgb2
  • Chain 'X':
    Compound: Ubiquitin D77
    Species: Homo sapiens [TaxId:9606]
    Gene: RPS27A, UBA80, UBCEP1, UBA52, UBCEP2, UBB, UBC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62988 (3-End)
      • expression tag (1-2)
    Domains in SCOPe 2.01: d3dvgx_
  • Chain 'Y':
    Compound: Ubiquitin
    Species: Homo sapiens [TaxId:9606]
    Gene: RPS27A, UBA80, UBCEP1, UBA52, UBCEP2, UBB, UBC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62988 (3-78)
      • engineered (65)
    Domains in SCOPe 2.01: d3dvgy_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3dvgA (A:)
sdiqmtqspsslsasvgdrvtitcrasqsvssavawyqqkpgkapklliysarslysgvp
srfsgsrsgtdftltisslqpedfatyycqqyssysslftfgqgtkveikrtvaapsvfi
fppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslss
tltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >3dvgA (A:)
tqspsslsasvgdrvtitcrasqsvssavawyqqkpgkapklliysarslysgvpsrfsg
srsgtdftltisslqpedfatyycqqyssysslftfgqgtkveikrtvaapsvfifppsd
eqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltls
kadyekhkvyacevthqglsspvtksfnrg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3dvgB (B:)
eisevqlvesggglvqpggslrlscaasgfnvktglihwvrqapgkglewvayitpyygs
tsyadsvkgrftisadtskntaylqmnslraedtavyycareyyrwytaidywgqgtlvt
vssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavl
qssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkth

    Sequence, based on observed residues (ATOM records): (download) 
    >3dvgB (B:)
evqlvesggglvqpggslrlscaasgfnvktglihwvrqapgkglewvayitpyygstsy
adsvkgrftisadtskntaylqmnslraedtavyycareyyrwytaidywgqgtlvtvss
astkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqss
glyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

  • Chain 'X':
    Sequence, based on SEQRES records: (download) 
    >3dvgX (X:)
gshmqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtls
dyniqkestlhlvlrlrggd

    Sequence, based on observed residues (ATOM records): (download) 
    >3dvgX (X:)
shmqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsd
yniqkestlhlvlrl

  • Chain 'Y':
    Sequence, based on SEQRES records: (download) 
    >3dvgY (Y:)
gshmqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtls
dyniqrestlhlvlrlrgg

    Sequence, based on observed residues (ATOM records): (download) 
    >3dvgY (Y:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqrestlhlvlrlrgg