PDB entry 3dqv
View 3dqv on RCSB PDB site
Description: Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation
Class: ligase
Keywords: ubiquitin, nedd8, scf, cullin-ring ligase, cullin, Nucleus, Ubl conjugation pathway, Host-virus interaction, Receptor, Ubl conjugation, Acetylation, Cytoplasm, DNA damage, DNA repair, Metal-binding, Zinc, Zinc-finger, SIGNALING PROTEIN
Deposited on
2008-07-09, released
2008-09-30
The last revision prior to the SCOPe 2.04 freeze date was dated
2009-02-24, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.249
AEROSPACI score: 0.19
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: nedd8
Species: Homo sapiens [TaxId:9606]
Gene: NEDD8
Database cross-references and differences (RAF-indexed):
- Uniprot Q15843 (5-80)
- insertion (3-4)
- conflict (66)
Domains in SCOPe 2.04: d3dqva_ - Chain 'B':
Compound: nedd8
Species: Homo sapiens [TaxId:9606]
Gene: NEDD8
Database cross-references and differences (RAF-indexed):
- Uniprot Q15843 (5-80)
- insertion (4)
- conflict (66)
Domains in SCOPe 2.04: d3dqvb_ - Chain 'C':
Compound: Cullin-5
Species: Homo sapiens [TaxId:9606]
Gene: CUL5, VACM1
Database cross-references and differences (RAF-indexed):
- Uniprot Q93034 (2-381)
- conflict (8)
- conflict (40-41)
- Chain 'D':
Compound: Cullin-5
Species: Homo sapiens [TaxId:9606]
Gene: CUL5, VACM1
Database cross-references and differences (RAF-indexed):
- Uniprot Q93034 (2-381)
- conflict (8)
- conflict (40-41)
- Chain 'R':
Compound: Rbx1
Species: Homo sapiens [TaxId:9606]
Gene: RBX1, RNF75, ROC1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d3dqvr_ - Chain 'Y':
Compound: Rbx1
Species: Homo sapiens [TaxId:9606]
Gene: RBX1, RNF75, ROC1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d3dqvy_ - Heterogens: ZN
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3dqvA (A:)
gsggsmlikvktltgkeieidieptdkverikerveekegippqqqrliysgkqmndekt
aadykimggsvlhlvlalrgg
Sequence, based on observed residues (ATOM records): (download)
>3dqvA (A:)
gsmlikvktltgkeieidieptdkverikerveekegippqqqrliysgkqmndektaad
ykimggsvlhlvlalrgg
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3dqvB (B:)
gsggsmlikvktltgkeieidieptdkverikerveekegippqqqrliysgkqmndekt
aadykimggsvlhlvlalrgg
Sequence, based on observed residues (ATOM records): (download)
>3dqvB (B:)
smlikvktltgkeieidieptdkverikerveekegippqqqrliysgkqmndektaady
kimggsvlhlvlalrgg
- Chain 'C':
No sequence available.
- Chain 'D':
No sequence available.
- Chain 'R':
Sequence, based on SEQRES records: (download)
>3dqvR (R:)
gsmdvdtpsgtnsgagkkrfevkkwnavalwawdivvdncaicrnhimdlciecqanqas
atseectvawgvcnhafhfhcisrwlktrqvcpldnrewefqkygh
Sequence, based on observed residues (ATOM records): (download)
>3dqvR (R:)
krfevkkwnavalwawdivvdncaicrnhimdlciecqanqasatseectvawgvcnhaf
hfhcisrwlktrqvcpldnrewefqk
- Chain 'Y':
Sequence, based on SEQRES records: (download)
>3dqvY (Y:)
gsmdvdtpsgtnsgagkkrfevkkwnavalwawdivvdncaicrnhimdlciecqanqas
atseectvawgvcnhafhfhcisrwlktrqvcpldnrewefqkygh
Sequence, based on observed residues (ATOM records): (download)
>3dqvY (Y:)
kkrfevkkwnavalwawdivvdncaicrnhimciecqanqasatseectvawgvcnhafh
fhcisrwlktrqvcpldnrewefqk