PDB entry 3dlg

View 3dlg on RCSB PDB site
Description: Crystal structure of hiv-1 reverse transcriptase in complex with GW564511.
Class: transferase
Keywords: HIV-1 REVERSE TRANSCRIPTASE, AIDS, NNRTI, GW564511, DRUG RESISTANCE, TRANSFERASE, Hydrolase
Deposited on 2008-06-27, released 2008-08-12
The last revision prior to the SCOP 1.75 freeze date was dated 2008-09-09, with a file datestamp of 2008-09-05.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.22
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Reverse transcriptase/ribonuclease H
    Species: HIV-1 M:B_HXB2R [TaxId:11706]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: p51 RT
    Species: HIV-1 M:B_HXB2R [TaxId:11706]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d3dlgb1
  • Heterogens: PO4, GWE, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3dlgB (B:)
    pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
    faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
    dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdivi
    yqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
    vqpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeae
    lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
    htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
    plvklwyqlekepivgaetf
    

    Sequence, based on observed residues (ATOM records): (download)
    >3dlgB (B:)
    tvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaiktk
    wrklvdfrelnkrtqdfphpaglkkkksvtvldvgdayfsvpldedfrkytaftipsinn
    etpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddlyvgsdleigq
    hrtkieelrqhllrwelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvr
    qlckllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqw
    tyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqket
    wetwwteywqatwipewefvntpplvklwyqlekepivga