PDB entry 3dle

View 3dle on RCSB PDB site
Description: Crystal structure of hiv-1 reverse transcriptase in complex with GF128590.
Class: transferase
Keywords: HIV-1 REVERSE TRANSCRIPTASE, AIDS, NNRTI, GF128590, DRUG RESISTANCE, Hydrolase, Transferase
Deposited on 2008-06-27, released 2008-08-12
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.214
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Reverse transcriptase/ribonuclease H
    Species: HIV-1 M:B_HXB2R [TaxId:11706]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: p51 RT
    Species: HIV-1 M:B_HXB2R [TaxId:11706]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d3dleb_
  • Heterogens: GFA, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3dleB (B:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdivi
yqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
plvklwyqlekepivgaetf

    Sequence, based on observed residues (ATOM records): (download) 
    >3dleB (B:)
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
kkdstkwrklvdfrelnkrtqdfgiphpaglkkkksvtvldvgdayfsvpldedfrkyta
ftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddlyv
gsdleigqhrtkieelrqhllrwelhpdkwtvqpivlpekdswtvndiqklvgklnwasq
iypgikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaei
qkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkf
klpiqketwetwwteywqatwipewefvntpplvklwyqleke