PDB entry 3dd3

View 3dd3 on RCSB PDB site
Description: Crystal Structure of the Glutathione Transferase Pi enzyme in complex with the bifunctional inhibitor, Etharapta
Class: transferase
Keywords: transferase, glutathione, detoxification, etharapta, ruthenium, rapta-c, ethacrynic-acid
Deposited on 2008-06-05, released 2009-04-21
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-12-07, with a file datestamp of 2011-12-02.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.2
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutathione S-transferase P
    Species: Homo sapiens [TaxId:9606]
    Gene: GSTP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3dd3a1, d3dd3a2
  • Chain 'B':
    Compound: Glutathione S-transferase P
    Species: Homo sapiens [TaxId:9606]
    Gene: GSTP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3dd3b1, d3dd3b2
  • Heterogens: MES, RUC, GSH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3dd3A (A:)
mppytvvyfpvrgrcaalrmlladqgqswkeevvtvetwqegslkasclygqlpkfqdgd
ltlyqsntilrhlgrtlglygkdqqeaalvdmvndgvedlrckyisliytnyeagkddyv
kalpgqlkpfetllsqnqggktfivgdqisfadynlldlllihevlapgcldafpllsay
vgrlsarpklkaflaspeyvnlpingngkq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3dd3B (B:)
mppytvvyfpvrgrcaalrmlladqgqswkeevvtvetwqegslkasclygqlpkfqdgd
ltlyqsntilrhlgrtlglygkdqqeaalvdmvndgvedlrckyisliytnyeagkddyv
kalpgqlkpfetllsqnqggktfivgdqisfadynlldlllihevlapgcldafpllsay
vgrlsarpklkaflaspeyvnlpingngkq

    Sequence, based on observed residues (ATOM records): (download) 
    >3dd3B (B:)
pytvvyfpvrgrcaalrmlladqgqswkeevvtvetwqegslkasclygqlpkfqdgdlt
lyqsntilrhlgrtlglygkdqqeaalvdmvndgvedlrckyisliytnyeagkddyvka
lpgqlkpfetllsqnqggktfivgdqisfadynlldlllihevlapgcldafpllsayvg
rlsarpklkaflaspeyvnlpingngkq