PDB entry 3dbd

View 3dbd on RCSB PDB site
Description: Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with Compound 094
Class: transferase
Keywords: Polo-like kinase 1, Plk1, catalytic domain, small-molecule inhibitor, Kinase, TRANSFERASE
Deposited on 2008-05-31, released 2008-10-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 3.05 Å
R-factor: 0.252
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Polo-like kinase 1
    Species: Danio rerio [TaxId:7955]
    Gene: PLK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3dbda_
  • Heterogens: 3FR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3dbdA (A:)
gplgsmsaaiakpsakpsahvdpksaplkeipdvlvdprtmkrymrgrflgkggfakcye
itdmdtkevfagkvvpksmllkphqkekmsteiaihksldnphvvgfhgffedddfvyvv
leicrrrsllelhkrrkavtepearyfmrqtiqgvqylhnnrvihrdlklgnlflnddmd
vkigdfglatkiefdgerkkdlcgtpnyiapevlckkghsfevdiwslgcilytllvgkp
pfetsclketyirikkneysvprhinpvasalirrmlhadptlrpsvaelltdefftsgy
apmrlptscltvpprfs

    Sequence, based on observed residues (ATOM records): (download) 
    >3dbdA (A:)
keipdvlvdprtmkrymrgrflgkggfakcyeitdmdtkevfagkvvpksmllkphqkek
msteiaihksldnphvvgfhgffedddfvyvvleicrrrsllelhkrrkavtepearyfm
rqtiqgvqylhnnrvihrdlklgnlflnddmdvkigdfglatkihsfevdiwslgcilyt
llvgkppfetsclketyirikkneysvprhinpvasalirrmlhadptlrpsvaelltde
fftsgyapmrlptscltvppr