PDB entry 3db8

View 3db8 on RCSB PDB site
Description: Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with Compound 041
Class: transferase
Keywords: Polo-like kinase 1, Plk1, catalytic domain, small-molecule inhibitor, Kinase, TRANSFERASE
Deposited on 2008-05-30, released 2008-10-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 3.15 Å
R-factor: 0.232
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Polo-like kinase 1
    Species: Danio rerio [TaxId:7955]
    Gene: PLK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3db8a_
  • Heterogens: 1FR

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3db8A (A:)
gplgsmsaaiakpsakpsahvdpksaplkeipdvlvdprtmkrymrgrflgkggfakcye
itdmdtkevfagkvvpksmllkphqkekmsteiaihksldnphvvgfhgffedddfvyvv
leicrrrsllelhkrrkavtepearyfmrqtiqgvqylhnnrvihrdlklgnlflnddmd
vkigdfglatkiefdgerkkdlcgtpnyiapevlckkghsfevdiwslgcilytllvgkp
pfetsclketyirikkneysvprhinpvasalirrmlhadptlrpsvaelltdefftsgy
apmrlptscltvpprfs

    Sequence, based on observed residues (ATOM records): (download) 
    >3db8A (A:)
keipdvlvdprtmkrymrgrflgkggfakcyeitdmdtkevfagkvvpksmllkphqkek
msteiaihksldnphvvgfhgffedddfvyvvleicrrrsllelhkrrkavtepearyfm
rqtiqgvqylhnnrvihrdlklgnlflnddmdvkigdfglatkihsfevdiwslgcilyt
llvgkppfetsclketyirikkneysvprhinpvasalirrmlhadptlrpsvaelltde
fftsgyapmrlptscltvppr