PDB entry 3d94

View 3d94 on RCSB PDB site
Description: Crystal structure of the insulin-like growth factor-1 receptor kinase in complex with PQIP
Class: transferase
Keywords: IGF1RK, receptor tyrosine kinase, PQIP, inhibitor, ATP-binding, Glycoprotein, Membrane, Nucleotide-binding, Phosphoprotein, Transferase, Transmembrane, Tyrosine-protein kinase
Deposited on 2008-05-26, released 2008-07-29
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.2
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Insulin-like growth factor 1 receptor beta chain
    Species: HOMO SAPIENS
    Gene: IGF1R
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08069 (0-End)
      • variant (256)
    Domains in SCOPe 2.02: d3d94a_
  • Heterogens: CA, D94, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3d94A (A:)
vyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmreri
eflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpemennpvla
ppslskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdy
yrkggkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfv
megglldkpdncpdmllelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseen
k

    Sequence, based on observed residues (ATOM records): (download) 
    >3d94A (A:)
vyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmreri
eflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpslskmiqma
geiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdyyrkggkgllpv
rwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfvmegglldkpdn
cpdmllelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseen