PDB entry 3d5w

View 3d5w on RCSB PDB site
Description: Crystal structure of a phosphorylated Polo-like kinase 1 (Plk1) catalytic domain in complex with ADP.
Class: transferase
Keywords: Polo-like kinase 1, Plk1, catalytic domain, small-molecule inhibitor, Kinase, TRANSFERASE
Deposited on 2008-05-17, released 2008-08-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.244
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Polo-like kinase 1
    Species: Danio rerio [TaxId:7955]
    Gene: PLK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3d5wa_
  • Heterogens: ADP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3d5wA (A:)
gplgsmsaaiakpsakpsahvdpksaplkeipdvlvdprtmkrymrgrflgkggfakcye
itdmdtkevfagkvvpksmllkphqkekmsteiaihksldnphvvgfhgffedddfvyvv
leicrrrsllelhkrrkavtepearyfmrqtiqgvqylhnnrvihrdlklgnlflnddmd
vkigdfglatkiefdgerkktlcgtpnyiapevlckkghsfevdiwslgcilytllvgkp
pfetsclketyirikkneysvprhinpvasalirrmlhadptlrpsvaelltdefftsgy
apmrlptscltvpprfs

    Sequence, based on observed residues (ATOM records): (download) 
    >3d5wA (A:)
keipdvlvdprtmkrymrgrflgkggfakcyeitdmdtkevfagkvvpksmlphqkekms
teiaihksldnphvvgfhgffedddfvyvvleicrrrsllelhkrrkavtepearyfmrq
tiqgvqylhnnrvihrdlklgnlflnddmdvkigdfglatkiefdgerkktlcgtpnyia
pevlckkghsfevdiwslgcilytllvgkppfetsclketyirikkneysvprhinpvas
alirrmlhadptlrpsvaelltdefftsgyapmrlptscltvppr